Theoretical studies on sRNA-mediated regulation in bacteria
文献类型：期刊论文
| 作者 | Chang, XX; Xu, LF; Shi, HL
|
| 刊名 | CHINESE PHYSICS B
 |
| 出版日期 | 2015 |
| 卷号 | 24期号:12页码:128703 |
| 关键词 | sRNA-mediated regulation kinetic model crosstalk |
| 通讯作者 | Xu, LF (reprint author), Jilin Univ, Dept Phys, Changchun 130012, Peoples R China. |
| 英文摘要 | Small RNA(sRNA)-mediated post-transcriptional regulation differs from protein-mediated regulation. Through base-pairing, sRNA can regulate the target mRNA in a catalytic or stoichiometric manner. Some theoretical models were built for comparison of the protein-mediated and sRNA-mediated modes in the steady-state behaviors and noise properties. Many experiments demonstrated that a single sRNA can regulate several mRNAs, which causes crosstalk between the targets. Here, we focus on some models in which two target mRNAs are silenced by the same sRNA to discuss their crosstalk features. Additionally, the sequence-function relationship of sRNA and its role in the kinetic process of base-pairing have been highlighted in model building. |
| 学科主题 | Physics |
| 类目[WOS] | Physics, Multidisciplinary |
| 关键词[WOS] | STOCHASTIC GENE-EXPRESSION ; SMALL NONCODING RNAS ; ESCHERICHIA-COLI ; MESSENGER-RNA ; INTRINSIC NOISE ; HFQ ; TARGET ; BINDING ; RIBOREGULATION ; ACCESSIBILITY |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://ir.itp.ac.cn/handle/311006/20770]  |
| 专题 | 理论物理研究所_理论物理所1978-2010年知识产出 |
| 推荐引用方式 GB/T 7714 | Chang, XX,Xu, LF,Shi, HL. Theoretical studies on sRNA-mediated regulation in bacteria[J]. CHINESE PHYSICS B,2015,24(12):128703. |
| APA | Chang, XX,Xu, LF,&Shi, HL.(2015).Theoretical studies on sRNA-mediated regulation in bacteria.CHINESE PHYSICS B,24(12),128703. |
| MLA | Chang, XX,et al."Theoretical studies on sRNA-mediated regulation in bacteria".CHINESE PHYSICS B 24.12(2015):128703. |
入库方式： OAI收割
来源：理论物理研究所
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