X-ray absorption near-edge structure study on the configuration of Cu2+/histidine complexes at different pH values
文献类型：期刊论文
| 作者 | Yu, MJ; Wang, Y; Xu, W |
| 刊名 | CHINESE PHYSICS B
 |
| 出版日期 | 2016 |
| 卷号 | 25期号:4页码:— |
| 关键词 | EXPERIMENTAL XANES SPECTRA COPPER-HISTIDINE THERAPY MENKES DISEASE MXAN CU2+ NI2+ ZN2+ CO2+ |
| ISSN号 | 1674-1056 |
| 通讯作者 | Yu, MJ (reprint author), Chinese Acad Sci, Inst High Energy Phys, Beijing 100049, Peoples R China. |
| 英文摘要 | The local configurations around metal ions in metalloproteins are of great significance for understanding their biological functions. Cu2+/histidine (His) is a typical complex existing in many metalloproteins and plays an important role in lots of physiological functions. The three-dimensional (3D) structural configurations of Cu2+/His complexes at different pH values (2.5, 6.5, and 8.5) are quantitatively determined by x-ray absorption near-edge structure (XANES). Generally Cu2+/His complex keeps an octahedral configuration consisting of oxygen atoms from water molecules and oxygen or nitrogen atoms from histidine molecules coordinated around Cu2+. It is proved in this work that the oxygen atoms from water molecules, when increasing the pH value from acid to basic value, are gradually substituted by the O-carboxyl, N-am, and N-im from hisitidine molecules. Furthermore, the symmetries of Cu2+/His complexes at pH 6.5 and pH 8.5 are found to be lower than at pH 2.5. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000375662600075 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/25893]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Yu, MJ,Wang, Y,Xu, W. X-ray absorption near-edge structure study on the configuration of Cu2+/histidine complexes at different pH values[J]. CHINESE PHYSICS B,2016,25(4):—. |
| APA | Yu, MJ,Wang, Y,&Xu, W.(2016).X-ray absorption near-edge structure study on the configuration of Cu2+/histidine complexes at different pH values.CHINESE PHYSICS B,25(4),—. |
| MLA | Yu, MJ,et al."X-ray absorption near-edge structure study on the configuration of Cu2+/histidine complexes at different pH values".CHINESE PHYSICS B 25.4(2016):—. |
入库方式： OAI收割
来源：上海应用物理研究所
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