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Multivariate Neural Representations of Value during Reward Anticipation and Consummation in the Human Orbitofrontal Cortex
文献类型：期刊论文
| 作者 | Yan, C; Su, L; Wang, Y; Xu, T; Yin, DZ; Fan, MX; Deng, CP; Hu, Y; Wang, ZX; Cheung, EFC |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2016 |
| 卷号 | 6页码:29878 |
| 关键词 | HUMAN BRAIN DECISION-MAKING NUCLEUS-ACCUMBENS TEMPORAL CORTEX FRONTAL-CORTEX VALENCE CONNECTIVITY MAGNITUDE MONETARY ANTERIOR |
| 通讯作者 | Chan, RCK (reprint author), Chinese Acad Sci, Neuropsychol & Appl Cognit Neurosci Lab, Key Lab Mental Hlth, Inst Psychol, Room 606,South Bldg,16 Lincui Rd, Beijing 100101, Peoples R China.,rckchan@psych.ac.cn |
| 英文摘要 | The role of the orbitofrontal cortex (OFC) in value processing is a focus of research. Conventional imaging analysis, where smoothing and averaging are employed, may not be sufficiently sensitive in studying the OFC, which has heterogeneous anatomical structures and functions. In this study, we employed representational similarity analysis (RSA) to reveal the multi-voxel fMRI patterns in the OFC associated with value processing during the anticipatory and the consummatory phases. We found that multi-voxel activation patterns in the OFC encoded magnitude and partial valence information (win vs. loss) but not outcome (favourable vs. unfavourable) during reward consummation. Furthermore, the lateral OFC rather than the medial OFC encoded loss information. Also, we found that OFC encoded values in a similar way to the ventral striatum (VS) or the anterior insula (AI) during reward anticipation regardless of motivated response and to the medial prefrontal cortex (MPFC) and the VS in reward consummation. In contrast, univariate analysis did not show changes of activation in the OFC. These findings suggest an important role of the OFC in value processing during reward anticipation and consummation. |
| WOS标题词 | Science & Technology - Other Topics |
| 学科主题 | Multidisciplinary Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000379189700001 |
| 源URL | [http://ir.sibs.ac.cn/handle/331001/4014]  |
| 专题 | 上海神经科学研究所_神经所(总) |
| 推荐引用方式 GB/T 7714 | Yan, C,Su, L,Wang, Y,et al. Multivariate Neural Representations of Value during Reward Anticipation and Consummation in the Human Orbitofrontal Cortex[J]. SCIENTIFIC REPORTS,2016,6:29878. |
| APA | Yan, C.,Su, L.,Wang, Y.,Xu, T.,Yin, DZ.,...&Chan, RCK.(2016).Multivariate Neural Representations of Value during Reward Anticipation and Consummation in the Human Orbitofrontal Cortex.SCIENTIFIC REPORTS,6,29878. |
| MLA | Yan, C,et al."Multivariate Neural Representations of Value during Reward Anticipation and Consummation in the Human Orbitofrontal Cortex".SCIENTIFIC REPORTS 6(2016):29878. |
入库方式： OAI收割
来源：上海神经科学研究所
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