Molecular weight controllable degradation of Laminaria japonica polysaccharides and its antioxidant properties
文献类型:期刊论文
作者 | Zha Shenghua1,2; Zhao Qingsheng1; Zhao Bing1; Ouyang Jie3; Mo Jianling3; Chen Jinjin1; Cao Lili1; Zhang Hong4 |
刊名 | JOURNAL OF OCEAN UNIVERSITY OF CHINA
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出版日期 | 2016-08-01 |
卷号 | 15期号:4页码:637-642 |
关键词 | Laminaria japonica polysaccharides degradation ultrasound |
ISSN号 | 1672-5182 |
英文摘要 | In this study, molecular weight controllable degradation of algal Laminaria japonica polysaccharides (LPS) was investigated by ultrasound combined with hydrogen peroxide. Three main factors, i.e., ultrasonic power (A), ultrasonic time (B), and H2O2 concentration (C) were chosen for optimizing parameters by employing three-factors, three-levels BBD. The influence of degradation on structure change and antioxidant activities was also investigated. A second-order polynomial equation including molecular weight (Y) of Laminaria japonica polysaccharides and each variable parameter, i.e., ultrasonic power (A), ultrasonic time (B), and H2O2 concentration (C), was established: Y=20718.67-4273.13A-4000.38B-1438.75C+2333.25AB+1511.00AC+873.00BC+2838.29A (2) + 2490.79B (2)+873.04C (2). The equation regression coefficient value (R (2) = 0.969) indicated that this equation was valid. The value of the adjusted determination coefficient (adjusted R (2) = 0.914) also confirmed that the model was highly significant. The results of selected experimental degradation conditions matched with the predicted value. FT-IR spectra revealed that the structures of LPS before and after degradation were not significantly changed. Antioxidant activities of LPS revealed that low Mws possessed stronger inhibitory than the original polysaccharides. The scavenging effects on superoxide radicals was the highest when IC50 of crude LPS was 4.92 mg mL(-1) and IC50 of Mw 18.576 KDa was 1.02 mg mL(-1), which was fourfold higher than initial polysaccharide. |
WOS标题词 | Science & Technology ; Physical Sciences |
类目[WOS] | Oceanography |
研究领域[WOS] | Oceanography |
关键词[WOS] | SULFATED POLYSACCHARIDES ; CHLOROPHYTA |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000379536300009 |
源URL | [http://ir.ipe.ac.cn/handle/122111/21251] ![]() |
专题 | 过程工程研究所_生化工程国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Beijing Forestry Univ, Coll Biol Sci & Biotechnol, Beijing 100083, Peoples R China 4.Beijing Tong Ren Tang Hlth Pharmaceut Co Ltd, Beijing 100085, Peoples R China |
推荐引用方式 GB/T 7714 | Zha Shenghua,Zhao Qingsheng,Zhao Bing,et al. Molecular weight controllable degradation of Laminaria japonica polysaccharides and its antioxidant properties[J]. JOURNAL OF OCEAN UNIVERSITY OF CHINA,2016,15(4):637-642. |
APA | Zha Shenghua.,Zhao Qingsheng.,Zhao Bing.,Ouyang Jie.,Mo Jianling.,...&Zhang Hong.(2016).Molecular weight controllable degradation of Laminaria japonica polysaccharides and its antioxidant properties.JOURNAL OF OCEAN UNIVERSITY OF CHINA,15(4),637-642. |
MLA | Zha Shenghua,et al."Molecular weight controllable degradation of Laminaria japonica polysaccharides and its antioxidant properties".JOURNAL OF OCEAN UNIVERSITY OF CHINA 15.4(2016):637-642. |
入库方式: OAI收割
来源:过程工程研究所
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