中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Molecular weight controllable degradation of Laminaria japonica polysaccharides and its antioxidant properties

文献类型:期刊论文

作者Zha Shenghua1,2; Zhao Qingsheng1; Zhao Bing1; Ouyang Jie3; Mo Jianling3; Chen Jinjin1; Cao Lili1; Zhang Hong4
刊名JOURNAL OF OCEAN UNIVERSITY OF CHINA
出版日期2016-08-01
卷号15期号:4页码:637-642
关键词Laminaria japonica polysaccharides degradation ultrasound
ISSN号1672-5182
英文摘要In this study, molecular weight controllable degradation of algal Laminaria japonica polysaccharides (LPS) was investigated by ultrasound combined with hydrogen peroxide. Three main factors, i.e., ultrasonic power (A), ultrasonic time (B), and H2O2 concentration (C) were chosen for optimizing parameters by employing three-factors, three-levels BBD. The influence of degradation on structure change and antioxidant activities was also investigated. A second-order polynomial equation including molecular weight (Y) of Laminaria japonica polysaccharides and each variable parameter, i.e., ultrasonic power (A), ultrasonic time (B), and H2O2 concentration (C), was established: Y=20718.67-4273.13A-4000.38B-1438.75C+2333.25AB+1511.00AC+873.00BC+2838.29A (2) + 2490.79B (2)+873.04C (2). The equation regression coefficient value (R (2) = 0.969) indicated that this equation was valid. The value of the adjusted determination coefficient (adjusted R (2) = 0.914) also confirmed that the model was highly significant. The results of selected experimental degradation conditions matched with the predicted value. FT-IR spectra revealed that the structures of LPS before and after degradation were not significantly changed. Antioxidant activities of LPS revealed that low Mws possessed stronger inhibitory than the original polysaccharides. The scavenging effects on superoxide radicals was the highest when IC50 of crude LPS was 4.92 mg mL(-1) and IC50 of Mw 18.576 KDa was 1.02 mg mL(-1), which was fourfold higher than initial polysaccharide.
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Oceanography
研究领域[WOS]Oceanography
关键词[WOS]SULFATED POLYSACCHARIDES ; CHLOROPHYTA
收录类别SCI
语种英语
WOS记录号WOS:000379536300009
源URL[http://ir.ipe.ac.cn/handle/122111/21251]  
专题过程工程研究所_生化工程国家重点实验室
作者单位1.Chinese Acad Sci, Inst Proc Engn, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Beijing Forestry Univ, Coll Biol Sci & Biotechnol, Beijing 100083, Peoples R China
4.Beijing Tong Ren Tang Hlth Pharmaceut Co Ltd, Beijing 100085, Peoples R China
推荐引用方式
GB/T 7714
Zha Shenghua,Zhao Qingsheng,Zhao Bing,et al. Molecular weight controllable degradation of Laminaria japonica polysaccharides and its antioxidant properties[J]. JOURNAL OF OCEAN UNIVERSITY OF CHINA,2016,15(4):637-642.
APA Zha Shenghua.,Zhao Qingsheng.,Zhao Bing.,Ouyang Jie.,Mo Jianling.,...&Zhang Hong.(2016).Molecular weight controllable degradation of Laminaria japonica polysaccharides and its antioxidant properties.JOURNAL OF OCEAN UNIVERSITY OF CHINA,15(4),637-642.
MLA Zha Shenghua,et al."Molecular weight controllable degradation of Laminaria japonica polysaccharides and its antioxidant properties".JOURNAL OF OCEAN UNIVERSITY OF CHINA 15.4(2016):637-642.

入库方式: OAI收割

来源:过程工程研究所

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