Traceable Nanoparticle Delivery of Small Interfering RNA and Retinoic Acid with Temporally Release Ability to Control Neural Stem Cell Differentiation for Alzheimer's Disease Therapy
文献类型：期刊论文
| 作者 | Zhang, Ran1,2; Li, Yan1; Hu, Bingbing1; Lu, Zhiguo1,3; Zhang, Jinchao2; Zhang, Xin1 |
| 刊名 | ADVANCED MATERIALS
 |
| 出版日期 | 2016-08-10 |
| 卷号 | 28期号:30页码:6345-+ |
| ISSN号 | 0935-9648 |
| 英文摘要 | Nanoparticles that can efficiently control the differentiation of neural stem cells (NSCs) into neurons are developed for Alzheimer's disease (AD) therapy. The treatment with these nanoparticles results in an attenuation of neuronal loss and rescues memory deficiencies in mice. The system can also be used to monitor the transplantation site, as well as the migration of NSCs in real time. Therefore, the system is proposed to open up new avenues for AD treatment. |
| WOS标题词 | Science & Technology ; Physical Sciences ; Technology |
| 类目[WOS] | Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| 研究领域[WOS] | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 关键词[WOS] | SIRNA DELIVERY ; IMPROVE COGNITION ; TRANSGENIC MODELS ; SMALL MOLECULES ; DRUG-DELIVERY ; BRAIN ; TRANSPLANTATION ; PROLIFERATION ; DERIVATIVES ; EFFICIENCY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000382480100006 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/21460]  |
| 专题 | 过程工程研究所_生化工程国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Hebei Univ, Key Lab Med Chem & Mol Diag, Minist Educ, Coll Chem & Environm Sci,Chem Biol Key Lab Hebei, Baoding 071002, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Ran,Li, Yan,Hu, Bingbing,et al. Traceable Nanoparticle Delivery of Small Interfering RNA and Retinoic Acid with Temporally Release Ability to Control Neural Stem Cell Differentiation for Alzheimer's Disease Therapy[J]. ADVANCED MATERIALS,2016,28(30):6345-+. |
| APA | Zhang, Ran,Li, Yan,Hu, Bingbing,Lu, Zhiguo,Zhang, Jinchao,&Zhang, Xin.(2016).Traceable Nanoparticle Delivery of Small Interfering RNA and Retinoic Acid with Temporally Release Ability to Control Neural Stem Cell Differentiation for Alzheimer's Disease Therapy.ADVANCED MATERIALS,28(30),6345-+. |
| MLA | Zhang, Ran,et al."Traceable Nanoparticle Delivery of Small Interfering RNA and Retinoic Acid with Temporally Release Ability to Control Neural Stem Cell Differentiation for Alzheimer's Disease Therapy".ADVANCED MATERIALS 28.30(2016):6345-+. |
入库方式： OAI收割
来源：过程工程研究所
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