Solvent-Regulated Asymmetric Hydrogenation of Quinoline Derivatives in Oligo(Ethylene Glycol)s through Host-Guest Interactions
文献类型：期刊论文
| 作者 | Wang, Tianli1,2; Chen, Ya1,2; Ouyang, Guanghui1,2; He, Yan-Mei1,2; Li, Zhiyan1,2; Fan, Qing-Hua1,2,3 |
| 刊名 | CHEMISTRY-AN ASIAN JOURNAL
 |
| 出版日期 | 2016-10-01 |
| 卷号 | 11期号:19页码:2773-2777 |
| 关键词 | asymmetric catalysis hydrogenation oligo(ethylene glycol)s ruthenium solvent effects |
| 英文摘要 | The asymmetric hydrogenation of quinolines in oligo(ethylene glycol)s (OEGs) and poly(ethylene glycol)s (PEGs) with chiral cationic ruthenium diamine complexes has been investigated. Interestingly, in liquid PEGs or long-chain OEGs, the Ru catalysts lost their reactivity. Upon the addition of a little MeOH, the hydrogenation of quinoline was switched "ON". Evidence from mass spectrometry and control experiments revealed that encapsulation of the quinolinium salt by PEG or long-chain OEG molecules through supramolecular interactions is possibly the main reason for such a switchable hydrogenation reaction. Moreover, the asymmetric hydrogenation of 2-substituted quinoline derivatives was achieved in triethylene glycol (3-OEG), thereby affording 1,2,3,4-tetrahydroquinolines with excellent reactivities and enantioselectivities (up to 99% ee). Furthermore, the Ru catalyst could be readily recycled for both pure 3-OEG and biphasic 3-OEG/n-hexane systems without a clear loss of reactivity and enantioselectivity. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/35126]  |
| 专题 | 化学研究所_分子识别与功能实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100190, Peoples R China 3.Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300072, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Tianli,Chen, Ya,Ouyang, Guanghui,et al. Solvent-Regulated Asymmetric Hydrogenation of Quinoline Derivatives in Oligo(Ethylene Glycol)s through Host-Guest Interactions[J]. CHEMISTRY-AN ASIAN JOURNAL,2016,11(19):2773-2777. |
| APA | Wang, Tianli,Chen, Ya,Ouyang, Guanghui,He, Yan-Mei,Li, Zhiyan,&Fan, Qing-Hua.(2016).Solvent-Regulated Asymmetric Hydrogenation of Quinoline Derivatives in Oligo(Ethylene Glycol)s through Host-Guest Interactions.CHEMISTRY-AN ASIAN JOURNAL,11(19),2773-2777. |
| MLA | Wang, Tianli,et al."Solvent-Regulated Asymmetric Hydrogenation of Quinoline Derivatives in Oligo(Ethylene Glycol)s through Host-Guest Interactions".CHEMISTRY-AN ASIAN JOURNAL 11.19(2016):2773-2777. |
入库方式： OAI收割
来源：化学研究所
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