Benzoic-Imine-Based Physiological-pH-Responsive Materials for Biomedical Applications
文献类型：期刊论文
| 作者 | Qu, Xiaozhong1,2; Yang, Zhenzhong1 |
| 刊名 | CHEMISTRY-AN ASIAN JOURNAL
 |
| 出版日期 | 2016-10-01 |
| 卷号 | 11期号:19页码:2633-2641 |
| 关键词 | benzoic imines biomedical applications drug delivery polymers responsive materials |
| 英文摘要 | The benzoic imine is a dynamic covalent bond, which is stable around neutral pH value (ca. 7.4), but starts to hydrolyze at the extracellular pH value of solid tumors (ca. 6.5) and rapidly disintegrates at endosome and lysosome pH values (ca. 4.5-6.5). This characteristic is promising for the construction of physiological-pH-responsive materials, such as polymeric micelles, nanoparticles, and hydrogels for pharmaceutical and tissue-engineering applications. This Focus Review summarizes recent progress in the design and synthesis of pH-sensitive materials that contain the benzoic imine bond with biomedical objectives. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/35115]  |
| 专题 | 化学研究所_高分子物理与化学实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qu, Xiaozhong,Yang, Zhenzhong. Benzoic-Imine-Based Physiological-pH-Responsive Materials for Biomedical Applications[J]. CHEMISTRY-AN ASIAN JOURNAL,2016,11(19):2633-2641. |
| APA | Qu, Xiaozhong,&Yang, Zhenzhong.(2016).Benzoic-Imine-Based Physiological-pH-Responsive Materials for Biomedical Applications.CHEMISTRY-AN ASIAN JOURNAL,11(19),2633-2641. |
| MLA | Qu, Xiaozhong,et al."Benzoic-Imine-Based Physiological-pH-Responsive Materials for Biomedical Applications".CHEMISTRY-AN ASIAN JOURNAL 11.19(2016):2633-2641. |
入库方式： OAI收割
来源：化学研究所
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