Extremely Stable Supramolecular Hydrogels Assembled from Nonionic Peptide Amphiphiles
文献类型：期刊论文
| 作者 | Wan, Yaoming1; Wang, Zuoning1; Sun, Jing2; Li, Zhibo1,2 |
| 刊名 | LANGMUIR
 |
| 出版日期 | 2016-08-02 |
| 卷号 | 32期号:30页码:7512-7518 |
| 英文摘要 | Peptide hydrogels with high stability in different media are of great interest in biomedical applications. In this paper, we report an easy, fast, and scalable method for preparing a family of nonionic peptide amphiphiles (PAs) obtained by direct aminolysis of alkyl-oilgo(gamma-benzyl-L-glutamate) samples, which were synthesized via the alkyl amine-initiated sequence ring-opening reaction of alpha-amino acid N-carboxyanhydrides. One great advantage of this method is that vast chemical diversity and large-scale yields can be achieved easily using commercially available hydramines. These PA samples can readily form a clear hydrogel without any external aid and show exceptionally enhanced gelation properties with a critical gelation concentration as low as 0.05 wt %. The hydrogels are highly stable against extreme pH values of 1 and 14 and a high salt concentration of 200 mM NaCl. These properties combined with the shear-thinning properties make these PA hydrogels ideal candidates for the new generation of injectable scaffolds. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/35264]  |
| 专题 | 化学研究所_高分子物理与化学实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci BNLMS, Beijing 100190, Peoples R China 2.Qingdao Univ Sci & Technol, Sch Polymer Sci & Engn, Qingdao 266042, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wan, Yaoming,Wang, Zuoning,Sun, Jing,et al. Extremely Stable Supramolecular Hydrogels Assembled from Nonionic Peptide Amphiphiles[J]. LANGMUIR,2016,32(30):7512-7518. |
| APA | Wan, Yaoming,Wang, Zuoning,Sun, Jing,&Li, Zhibo.(2016).Extremely Stable Supramolecular Hydrogels Assembled from Nonionic Peptide Amphiphiles.LANGMUIR,32(30),7512-7518. |
| MLA | Wan, Yaoming,et al."Extremely Stable Supramolecular Hydrogels Assembled from Nonionic Peptide Amphiphiles".LANGMUIR 32.30(2016):7512-7518. |
入库方式： OAI收割
来源：化学研究所
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