High-speed intravascular photoacoustic imaging at 1.7 mu m with a KTP-based OPO
文献类型：期刊论文
| 作者 | Hui, Jie; Yu, Qianhuan; Ma, Teng; Wang, Pu; Cao, Yingchun; Bruning, Rebecca S.; Qu, Yueqiao; Chen, Zhongping; Zhou, Qifa; Sturek, Michael |
| 刊名 | biomed. opt. express
 |
| 出版日期 | 2015 |
| 卷号 | 6期号:11页码:4557 |
| 通讯作者 | hui, j (reprint author), purdue univ, dept phys & astron, w lafayette, in 47906 usa. |
| 英文摘要 | lipid deposition inside the arterial wall is a hallmark of plaque vulnerability. based on overtone absorption of c-h bonds, intravascular photoacoustic (ivpa) catheter is a promising technology for quantifying the amount of lipid and its spatial distribution inside the arterial wall. thus far, the clinical translation of ivpa technology is limited by its slow imaging speed due to lack of a high-pulse-energy high-repetition-rate laser source for lipid-specific first overtone excitation at 1.7 mu m. here, we demonstrate a potassium titanyl phosphate (ktp)-based optical parametric oscillator with output pulse energy up to 2 mj at a wavelength of 1724 nm and with a repetition rate of 500 hz. using this laser and a ring-shape transducer, ivpa imaging at speed of 1 frame per sec was demonstrated. performance of the ivpa imaging system's resolution, sensitivity, and specificity were characterized by carbon fiber and a lipid-mimicking phantom. the clinical utility of this technology was further evaluated ex vivo in an excised atherosclerotic human femoral artery with comparison to histology. (c) 2015 optical society of america |
| 收录类别 | SCI |
| 语种 | 英语 |
| 版本 | 出版稿 |
| 源URL | [http://ir.siom.ac.cn/handle/181231/13954]  |
| 专题 | 上海光学精密机械研究所_空间激光信息技术研究中心 |
| 作者单位 | 1.[Hui, Jie] Purdue Univ, Dept Phys & Astron, W Lafayette, IN 47906 USA 2.[Yu, Qianhuan 3.Chen, Weibiao] Chinese Acad Sci, Shanghai Inst Opt & Fine Mech, Key Lab Space Laser Commun & Detect Technol, Shanghai 201800, Peoples R China 4.[Yu, Qianhuan] Univ Chinese Acad Sci, Beijing 100049, Peoples R China 5.[Ma, Teng 6.Zhou, Qifa] Univ So Calif, Dept Biomed Engn, NIH Ultrason Transducer Resource Ctr, Los Angeles, CA 90089 USA 7.[Wang, Pu 8.Cao, Yingchun 9.Cheng, Ji-Xin] Purdue Univ, Weldon Sch Biomed Engn, W Lafayette, IN 47906 USA 10.[Bruning, Rebecca S. |
| 推荐引用方式 GB/T 7714 | Hui, Jie,Yu, Qianhuan,Ma, Teng,et al. High-speed intravascular photoacoustic imaging at 1.7 mu m with a KTP-based OPO[J]. biomed. opt. express,2015,6(11):4557. |
| APA | Hui, Jie.,Yu, Qianhuan.,Ma, Teng.,Wang, Pu.,Cao, Yingchun.,...&Chen, Weibiao.(2015).High-speed intravascular photoacoustic imaging at 1.7 mu m with a KTP-based OPO.biomed. opt. express,6(11),4557. |
| MLA | Hui, Jie,et al."High-speed intravascular photoacoustic imaging at 1.7 mu m with a KTP-based OPO".biomed. opt. express 6.11(2015):4557. |
入库方式： OAI收割
来源：上海光学精密机械研究所
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