Dog chromosome-specific paints reveal evolutionary inter- and intrachromosomal rearrangements in the American mink and human
文献类型：期刊论文
| 作者 | Graphodatsky AS1; Yang F[*]2,3; Serdukova N1; Perelman P1; Zhdanova NS1; Ferguson-Smith MA3 |
| 刊名 | CYTOGENETICS AND CELL GENETICS
 |
| 出版日期 | 2000 |
| 卷号 | 90期号:3-4页码:275-278 |
| ISSN号 | 0301-0171 |
| 通讯作者 | fy@mole.bio.cam.ac.uk |
| 合作状况 | 其它 |
| 英文摘要 | Forty chromosome-specific paint probes of the domestic dog (Canis familiaris, 2n = 78) were used to delineate conserved segments on metaphase chromosomes of the American mink (Mustela vison, 2n = 30) by fluorescence in situ hybridisation. Half of the 38 canine autosomal probes each painted one pair of homologous segments in a diploid mink metaphase, whereas the other 19 dog probes each painted from two to five pairs of discrete segments. In total, 38 canine autosomal paints highlighted 71 pairs of conserved segments in the mink. These painting results allow us to establish a complete comparative chromosome map between the American mink and domestic dog. This map demonstrates that extensive chromosome rearrangements differentiate the karyotypes of the dog and American mink. The 38 dog autosomes could be reconstructed from the 14 autosomes of the American mink through at least 47 fissions, 25 chromosome fusions, and six inversions. Furthermore, comparison of the current dog/mink map with the published human/dog map discloses 23 cryptic intrachromosomal rearrangements in 10 regions of conserved synteny in the human and American mink genomes and thus further refined the human/mink comparative genome map. |
| 收录类别 | SCI |
| 资助信息 | A.S.G. and N.Z. are supported by research grants from the Russian Fund for Basic Research. |
| 原文出处 | 200090275.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/2001]  |
| 专题 | 昆明动物研究所_其他 |
| 作者单位 | 1.Institute of Cytology and Genetics, Novosibirsk (Russia) 2.Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, Yunnan (People’s Republic of China) 3.Centre for Veterinary Science, Department of Clinical Veterinary Medicine, University of Cambridge, Cambridge (UK) |
| 推荐引用方式 GB/T 7714 | Graphodatsky AS,Yang F[*],Serdukova N,et al. Dog chromosome-specific paints reveal evolutionary inter- and intrachromosomal rearrangements in the American mink and human[J]. CYTOGENETICS AND CELL GENETICS,2000,90(3-4):275-278. |
| APA | Graphodatsky AS,Yang F[*],Serdukova N,Perelman P,Zhdanova NS,&Ferguson-Smith MA.(2000).Dog chromosome-specific paints reveal evolutionary inter- and intrachromosomal rearrangements in the American mink and human.CYTOGENETICS AND CELL GENETICS,90(3-4),275-278. |
| MLA | Graphodatsky AS,et al."Dog chromosome-specific paints reveal evolutionary inter- and intrachromosomal rearrangements in the American mink and human".CYTOGENETICS AND CELL GENETICS 90.3-4(2000):275-278. |
入库方式： OAI收割
来源：昆明动物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。