Conserved chromosome segments in Hylobates hoolock revealed by human and H-leucogenys paint probes
文献类型:期刊论文
作者 | Nie W1; Rens W2; Wang J1; Yang F[*]2 |
刊名 | CYTOGENETICS AND CELL GENETICS
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出版日期 | 2001 |
卷号 | 92期号:3-4页码:248-253 |
ISSN号 | 0301-0171 |
通讯作者 | fy@mole.bio.cam.ac.uk |
英文摘要 | A complete comparative chromosome map of the white-browed gibbon (Hylobates hoolock, 2n = 38), white-cheeked gibbon (Hylobates leucogenys, 2n = 52), and human has been established by hybridising H. leucogenys chromosome-specific paints and human 24-colour paints onto H. hoolock metaphase chromosomes. In the 18 H. hoolock autosomes, we identified 62 conserved segments that showed DNA homology to regions of the 25 H. leucogenys autosomes, Numerous interchromosomal rearrangements differentiate the karyotypes of H. leucogenys and H. hoolock. Only H. hoolock chromosome 10 showed homology to one entire autosome of H. leucogenys. The hybridisation of human 24-colour paints not only confirmed most of the chromosome correspondences between human and H. hoolock established previously but also helped to correct five erroneous assignments and revealed three new segments. Our results demonstrate that the karyotypes of the extant gibbons have arisen mainly through extensive translocation events and that the karyotype of H. hoolock more closely resembles the ancestral karyotype of Hylobates, rather than the karyotype of H. leucogenys. |
收录类别 | SCI |
资助信息 | Supported in part by the Bai Ren Ji Hua fund of the Chinese Academy of Sciences |
原文出处 | 200192248.pdf |
语种 | 英语 |
公开日期 | 2010-08-24 |
源URL | [http://159.226.149.42:8088/handle/152453/2003] ![]() |
专题 | 昆明动物研究所_保护遗传学(细胞库) |
作者单位 | 1.Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, Yunnan (Peoples Republic of China) 2.Centre for Veterinary Science, Department of Clinical Veterinary Medicine, University of Cambridge, Cambridge (UK) |
推荐引用方式 GB/T 7714 | Nie W,Rens W,Wang J,et al. Conserved chromosome segments in Hylobates hoolock revealed by human and H-leucogenys paint probes[J]. CYTOGENETICS AND CELL GENETICS,2001,92(3-4):248-253. |
APA | Nie W,Rens W,Wang J,&Yang F[*].(2001).Conserved chromosome segments in Hylobates hoolock revealed by human and H-leucogenys paint probes.CYTOGENETICS AND CELL GENETICS,92(3-4),248-253. |
MLA | Nie W,et al."Conserved chromosome segments in Hylobates hoolock revealed by human and H-leucogenys paint probes".CYTOGENETICS AND CELL GENETICS 92.3-4(2001):248-253. |
入库方式: OAI收割
来源:昆明动物研究所
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