中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Conserved chromosome segments in Hylobates hoolock revealed by human and H-leucogenys paint probes

文献类型:期刊论文

作者Nie W1; Rens W2; Wang J1; Yang F[*]2
刊名CYTOGENETICS AND CELL GENETICS
出版日期2001
卷号92期号:3-4页码:248-253
ISSN号0301-0171
通讯作者fy@mole.bio.cam.ac.uk
英文摘要A complete comparative chromosome map of the white-browed gibbon (Hylobates hoolock, 2n = 38), white-cheeked gibbon (Hylobates leucogenys, 2n = 52), and human has been established by hybridising H. leucogenys chromosome-specific paints and human 24-colour paints onto H. hoolock metaphase chromosomes. In the 18 H. hoolock autosomes, we identified 62 conserved segments that showed DNA homology to regions of the 25 H. leucogenys autosomes, Numerous interchromosomal rearrangements differentiate the karyotypes of H. leucogenys and H. hoolock. Only H. hoolock chromosome 10 showed homology to one entire autosome of H. leucogenys. The hybridisation of human 24-colour paints not only confirmed most of the chromosome correspondences between human and H. hoolock established previously but also helped to correct five erroneous assignments and revealed three new segments. Our results demonstrate that the karyotypes of the extant gibbons have arisen mainly through extensive translocation events and that the karyotype of H. hoolock more closely resembles the ancestral karyotype of Hylobates, rather than the karyotype of H. leucogenys.
收录类别SCI
资助信息Supported in part by the Bai Ren Ji Hua fund of the Chinese Academy of Sciences
原文出处200192248.pdf
语种英语
公开日期2010-08-24
源URL[http://159.226.149.42:8088/handle/152453/2003]  
专题昆明动物研究所_保护遗传学(细胞库)
作者单位1.Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, Yunnan (Peoples Republic of China)
2.Centre for Veterinary Science, Department of Clinical Veterinary Medicine, University of Cambridge, Cambridge (UK)
推荐引用方式
GB/T 7714
Nie W,Rens W,Wang J,et al. Conserved chromosome segments in Hylobates hoolock revealed by human and H-leucogenys paint probes[J]. CYTOGENETICS AND CELL GENETICS,2001,92(3-4):248-253.
APA Nie W,Rens W,Wang J,&Yang F[*].(2001).Conserved chromosome segments in Hylobates hoolock revealed by human and H-leucogenys paint probes.CYTOGENETICS AND CELL GENETICS,92(3-4),248-253.
MLA Nie W,et al."Conserved chromosome segments in Hylobates hoolock revealed by human and H-leucogenys paint probes".CYTOGENETICS AND CELL GENETICS 92.3-4(2001):248-253.

入库方式: OAI收割

来源:昆明动物研究所

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