Karyotypic relationships of horses and zebras: results of cross-species chromosome painting
文献类型：期刊论文
| 作者 | Yang F[*]1,2; Fu B1; O'Brien PCM1; Robinson TJ3; Ryder OA4; Ferguson-Smith MA1 |
| 刊名 | CYTOGENETIC AND GENOME RESEARCH
 |
| 出版日期 | 2003 |
| 卷号 | 102期号:1-4页码:235-243 |
| ISSN号 | 1424-8581 |
| 通讯作者 | fy@mole.bio.cam.ac.uk |
| 合作状况 | 其它 |
| 英文摘要 | Complete sets of chromosome-specific painting probes, derived from flow-sorted chromosomes of human (HSA), Equus caballus (ECA) and Equus burchelli (EBU) were used to delineate conserved chromosomal segments between human and Equits burchelli, and among four equid species, E. przewalskii (EPR), E. caballus, E. burchelli and E. zebra hartmannae (EZH) by cross-species chromosome painting. Genome-wide comparative maps between these species have been established. Twenty-two human autosomal probes revealed 48 conserved segments in E. burchelli. The adjacent segment combinations HSA3/21, 7/16p, 16q/19q, 14/15, 12/22 and 4/8, presumed ancestral syntenies for all eutherian mammals, were also found conserved in E. burchelli. The comparative maps of equids allow for the unequivocal characterization of chromosomal rearrangements that differentiate the karyotypes of these equid species. The karyotypes of E. przewalskii and E. caballus differ by one Robertsonian translocation (ECA5 = EPR23 + EPR24); numerous Robertsonian translocations and tandem fusions and several inversions account for the karyotypic differences between the horses and zebras. Our results shed new light on the karyotypic evolution of Equidae. |
| 收录类别 | SCI |
| 资助信息 | This study was partially supported by grants from the China National Natural Science Foundation and Chinese Academy of Sciences to F.Y. and grants from the Well- come Trust to M.A.F.-S. and T.J.R. |
| 原文出处 | 2003102235.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/2009]  |
| 专题 | 昆明动物研究所_其他 昆明动物研究所_细胞与分子进化重点实验室 |
| 作者单位 | 1.Centre for Veterinary Science, University of Cambridge, Cambridge (UK) 2.Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, Yunnan (PR China) 3.Evolutionary Genomics Group, Department of Zoology, University of Stellenbosch, Stellenbosch (South Africa) 4.The Zoological Society of San Diego, Centre for Reproduction of Endangered Species, San Diego, CA (USA) |
| 推荐引用方式 GB/T 7714 | Yang F[*],Fu B,O'Brien PCM,et al. Karyotypic relationships of horses and zebras: results of cross-species chromosome painting[J]. CYTOGENETIC AND GENOME RESEARCH,2003,102(1-4):235-243. |
| APA | Yang F[*],Fu B,O'Brien PCM,Robinson TJ,Ryder OA,&Ferguson-Smith MA.(2003).Karyotypic relationships of horses and zebras: results of cross-species chromosome painting.CYTOGENETIC AND GENOME RESEARCH,102(1-4),235-243. |
| MLA | Yang F[*],et al."Karyotypic relationships of horses and zebras: results of cross-species chromosome painting".CYTOGENETIC AND GENOME RESEARCH 102.1-4(2003):235-243. |
入库方式： OAI收割
来源：昆明动物研究所
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