Reciprocal chromosome painting among human, aardvark, and elephant (superorder Afrotheria) reveals the likely eutherian ancestral karyotype
文献类型：期刊论文
| 作者 | Yang F1,2; Alkalaeva EZ3; Perelman PL3; Pardini AT4; Harrison WR4; O'Brien PCM1; Fu B1; Graphodatsky AS3; Ferguson-Smith MA1; Robinson TJ[*]4 |
| 刊名 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
 |
| 出版日期 | 2003 |
| 卷号 | 100期号:3页码:1062-1066 |
| ISSN号 | 0027-8424 |
| 通讯作者 | tjr@sun.ac.za |
| 合作状况 | 其它 |
| 英文摘要 | The Afrotheria, a supraordinal grouping of mammals whose radiation is rooted in Africa, is strongly supported by DNA sequence data but not by their disparate anatomical features. We have used flow-sorted human, aardvark, and African elephant chromosome painting probes and applied reciprocal painting schemes to representatives of two of the Afrotherian orders, the Tubulidentata (aardvark) and Proboscidea (elephants), in an attempt to shed additional light on the evolutionary affinities of this enigmatic group of mammals. Although we have not yet found any unique cytogenetic signatures that support the monophyly of the Afrotheria, embedded within the aardvark genome we find the strongest evidence yet of a mammalian ancestral karyotype comprising 2n = 44. This karyotype includes nine chromosomes that show complete conserved synteny to those of man, six that show conservation as single chromosome arms or blocks in the human karyotype but that occur on two different chromosomes in the ancestor, and seven neighbor-joining combinations (i.e., the synteny is maintained in the majority of species of the orders studied so far, but which corresponds to two chromosomes in humans). The comparative chromosome maps presented between human and these Afrotherian species provide further insight into mammalian genome organization and comparative genomic data for the Afrotheria, one of the four major evolutionary clades postulated for the Eutheria. |
| 收录类别 | SCI |
| 资助信息 | This study was funded in part by a Wellcome Trust Collaborative Research Initiative Grant (to T.J.R. and M.A.F.-S.), the South African National Research Foundation (to T.J.R.), the National Natural Science Foundation of China and the Chinese Academy of Sciences (to F.Y.), the Russian Fund of Basic Research (to A.S.G., P.L.P., and E.Z.A.), and Grant 01-2163 from the International Association for the Promotion of Co-operation with Scientists from the New Independent States of the Former Soviet Union (to A.S.G. and M.A.F.-S.). |
| 原文出处 | 20031001062.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/2013]  |
| 专题 | 昆明动物研究所_其他 |
| 作者单位 | 1.Centre for Veterinary Science, University of Cambridge, Cambridge CB3 0ES, United Kingdom 2.Kunming Institute of Zoology, The Chinese Academy of Sciences, Yunnan 650223, People’s Republic of China 3.Institute of Cytology and Genetics, Novosibirsk 630090, Russia 4.Department of Zoology, University of Stellenbosch, Private Bag X1, Matieland 7602, South Africa |
| 推荐引用方式 GB/T 7714 | Yang F,Alkalaeva EZ,Perelman PL,et al. Reciprocal chromosome painting among human, aardvark, and elephant (superorder Afrotheria) reveals the likely eutherian ancestral karyotype[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2003,100(3):1062-1066. |
| APA | Yang F.,Alkalaeva EZ.,Perelman PL.,Pardini AT.,Harrison WR.,...&Robinson TJ[*].(2003).Reciprocal chromosome painting among human, aardvark, and elephant (superorder Afrotheria) reveals the likely eutherian ancestral karyotype.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,100(3),1062-1066. |
| MLA | Yang F,et al."Reciprocal chromosome painting among human, aardvark, and elephant (superorder Afrotheria) reveals the likely eutherian ancestral karyotype".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100.3(2003):1062-1066. |
入库方式： OAI收割
来源：昆明动物研究所
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