Refined genome-wide comparative map of the domestic horse, donkey and human based on cross-species chromosome painting: insight into the occasional fertility of mules
文献类型：期刊论文
| 作者 | Yang FT[*]1,2; Fu BY1; O'Brien PCM1; Nie WH2; Ryder OA3; Ferguson-Smith MA1 |
| 刊名 | CHROMOSOME RESEARCH
 |
| 出版日期 | 2004 |
| 卷号 | 12期号:1页码:65-76 |
| 关键词 | chromosome painting donkey Equus flow sorting horse human |
| ISSN号 | 0967-3849 |
| 通讯作者 | fy@mole.bio.cam.uk |
| 合作状况 | 其它 |
| 英文摘要 | We have made a complete set of painting probes for the domestic horse by degenerate oligonucleotide-primed PCR amplification of flow-sorted horse chromosomes. The horse probes, together with a full set of those available for human, were hybridized onto metaphase chromosomes of human, horse and mule. Based on the hybridization results, we have generated genome-wide comparative chromosome maps involving the domestic horse, donkey and human. These maps define the overall distribution and boundaries of evolutionarily conserved chromosomal segments in the three genomes. Our results shed further light on the karyotypic relationships among these species and, in particular, the chromosomal rearrangements that underlie hybrid sterility and the occasional fertility of mules. |
| 收录类别 | SCI |
| 资助信息 | This work was partially supported by grants to F.Y. from the China National Natural Science Foundation and Chinese Academy of Sciences and grants to M.A.F.-S. from the Wellcome Trust. |
| 原文出处 | 20041265.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/2017]  |
| 专题 | 昆明动物研究所_保护遗传学(细胞库) |
| 作者单位 | 1.Centre for Veterinary Science, University of Cambridge, Cambridge CB3 0ES, UK 2.Kunming Institute of Zoology, The Chinese Academy of Science, Kunming, Yunnan, Peoples Republic of China 3.The Zoological Society of San Diego, Centre for Reproduction of Endangered Species, San Diego, CA, USA |
| 推荐引用方式 GB/T 7714 | Yang FT[*],Fu BY,O'Brien PCM,et al. Refined genome-wide comparative map of the domestic horse, donkey and human based on cross-species chromosome painting: insight into the occasional fertility of mules[J]. CHROMOSOME RESEARCH,2004,12(1):65-76. |
| APA | Yang FT[*],Fu BY,O'Brien PCM,Nie WH,Ryder OA,&Ferguson-Smith MA.(2004).Refined genome-wide comparative map of the domestic horse, donkey and human based on cross-species chromosome painting: insight into the occasional fertility of mules.CHROMOSOME RESEARCH,12(1),65-76. |
| MLA | Yang FT[*],et al."Refined genome-wide comparative map of the domestic horse, donkey and human based on cross-species chromosome painting: insight into the occasional fertility of mules".CHROMOSOME RESEARCH 12.1(2004):65-76. |
入库方式： OAI收割
来源：昆明动物研究所
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