Defining the orientation of the tandem fusions that occurred during the evolution of Indian muntjac chromosomes by BAC mapping
文献类型：期刊论文
| 作者 | Chi JX1,2; Huang L1,2; Nie W1; Wang J1; Su B1; Yang F[*]1,3,4 |
| 刊名 | CHROMOSOMA
 |
| 出版日期 | 2005 |
| 卷号 | 114期号:3页码:167-172 |
| ISSN号 | 0009-5915 |
| 通讯作者 | kcb@mail.kiz.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | The Indian muntjac (Muntiacus muntjak vaginalis) has a karyotype of 2n=6 in the female and 7 in the male, the karyotypic evolution of which through extensive tandem fusions and several centric fusions has been well-documented by recent molecular cytogenetic studies. In an attempt to define the fusion orientations of conserved chromosomal segments and the molecular mechanisms underlying the tandem fusions, we have constructed a highly redundant (more than six times of whole genome coverage) bacterial artificial chromosome (BAC) library of Indian muntjac. The BAC library contains 124,800 clones with no chromosome bias and has an average insert DNA size of 120 kb. A total of 223 clones have been mapped by fluorescent in situ hybridization onto the chromosomes of both Indian muntjac and Chinese muntjac and a high-resolution comparative map has been established. Our mapping results demonstrate that all tandem fusions that occurred during the evolution of Indian muntjac karyotype from the acrocentric 2n=70 hypothetical ancestral karyotype are centromere-telomere (head-tail) fusions. |
| 收录类别 | SCI |
| 资助信息 | This research is supported by the National Natural Science Foundation of China (No. 30170506). |
| 原文出处 | 2005114167.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/2129]  |
| 专题 | 昆明动物研究所_比较基因组学 昆明动物研究所_保护遗传学(细胞库) 昆明动物研究所_细胞与分子进化重点实验室 |
| 作者单位 | 1.Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, The Chinese Academy of Sciences 2.Graduate School of the Chinese Academy of Sciences, Beijing, 100039, People’s Republic of China 3.Centre for Veterinary Science, University of Cambridge, Madingley Road, Cambridge, CB3 0ES, UK 4.Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK |
| 推荐引用方式 GB/T 7714 | Chi JX,Huang L,Nie W,et al. Defining the orientation of the tandem fusions that occurred during the evolution of Indian muntjac chromosomes by BAC mapping[J]. CHROMOSOMA,2005,114(3):167-172. |
| APA | Chi JX,Huang L,Nie W,Wang J,Su B,&Yang F[*].(2005).Defining the orientation of the tandem fusions that occurred during the evolution of Indian muntjac chromosomes by BAC mapping.CHROMOSOMA,114(3),167-172. |
| MLA | Chi JX,et al."Defining the orientation of the tandem fusions that occurred during the evolution of Indian muntjac chromosomes by BAC mapping".CHROMOSOMA 114.3(2005):167-172. |
入库方式： OAI收割
来源：昆明动物研究所
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