Comparative genomic analysis links karyotypic evolution with genomic evolution in the Indian Muntjac (Muntiacus muntjak vaginalis)
文献类型：期刊论文
| 作者 | Zhou Q1,3; Huang L2,3; Zhang JG4; Zhao XY1; Zhang QP4; Song F4; Chi JX2,3; Yang FT[*]2,5; Wang W[*]1 |
| 刊名 | CHROMOSOMA
 |
| 出版日期 | 2006 |
| 卷号 | 115期号:6页码:427-436 |
| ISSN号 | 0009-5915 |
| 通讯作者 | fy1@sanger.ac.uk ; wwang@mail.kiz.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | The karyotype of Indian muntjacs (Muntiacus muntjak vaginalis) has been greatly shaped by chromosomal fusion, which leads to its lowest diploid number among the extant known mammals. We present, here, comparative results based on draft sequences of 37 bacterial artificial clones (BAC) clones selected by chromosome painting for this special muntjac species. Sequence comparison on these BAC clones uncovered sequence syntenic relationships between the muntjac genome and those of other mammals. We found that the muntjac genome has peculiar features with respect to intron size and evolutionary rates of genes. Inspection of more than 80 pairs of orthologous introns from 15 genes reveals a significant reduction in intron size in the Indian muntjac compared to that of human, mouse, and dog. Evolutionary analysis using 19 genes indicates that the muntjac genes have evolved rapidly compared to other mammals. In addition, we identified and characterized sequence composition of the first BAC clone containing a chromosomal fusion site. Our results shed new light on the genome architecture of the Indian muntjac and suggest that chromosomal rearrangements have been accompanied by other salient genomic changes. |
| 收录类别 | SCI |
| 资助信息 | This research was supported by key project grants of the Key Laboratory of Cellular and Molecular Evolution in Kunming Institute of Zoology and the National Natural Science Foundation of China (No. 30170506). |
| 原文出处 | 2006115427.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/4813]  |
| 专题 | 昆明动物研究所_基因起源组 昆明动物研究所_其他 昆明动物研究所_细胞与分子进化重点实验室 |
| 作者单位 | 1.CAS-Max Planck Junior Research Group, Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, #32 E. Jiao Chang Road, Kunming, Yunnan 650223, People’s Republic of China 2.Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, People’s Republic of China 3.Graduate School of Chinese Academy Sciences, Beijing 100039, People’s Republic of China 4.Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100039, People’s Republic of China 5.Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK |
| 推荐引用方式 GB/T 7714 | Zhou Q,Huang L,Zhang JG,et al. Comparative genomic analysis links karyotypic evolution with genomic evolution in the Indian Muntjac (Muntiacus muntjak vaginalis)[J]. CHROMOSOMA,2006,115(6):427-436. |
| APA | Zhou Q.,Huang L.,Zhang JG.,Zhao XY.,Zhang QP.,...&Wang W[*].(2006).Comparative genomic analysis links karyotypic evolution with genomic evolution in the Indian Muntjac (Muntiacus muntjak vaginalis).CHROMOSOMA,115(6),427-436. |
| MLA | Zhou Q,et al."Comparative genomic analysis links karyotypic evolution with genomic evolution in the Indian Muntjac (Muntiacus muntjak vaginalis)".CHROMOSOMA 115.6(2006):427-436. |
入库方式： OAI收割
来源：昆明动物研究所
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