Genome-Wide Comparative Chromosome Map between Human and the Forrest's Pika (Ochotona forresti) Established by Cross-Species Chromosome Painting: Further Support for the Glires Hypothesis
文献类型：期刊论文
| 作者 | Ye J[*]1,2; Nie WH1; Graphodatsky AS4; Yang F5; Wang J1; Su W1; Jing M3 |
| 刊名 | CYTOGENETIC AND GENOME RESEARCH
 |
| 出版日期 | 2011 |
| 卷号 | 132期号:1-2页码:41-46 |
| 关键词 | Chromosome painting Evolution Forrest's pika Lagomorpha Mapping Rabbit |
| 通讯作者 | yjpyyjjpp@hotmail.com |
| 合作状况 | 其它 |
| 英文摘要 | Comparative genomic data for ochotonids (pikas) are important for understanding the karyotype evolution of lagomorphs. Here, we have established the first genome-wide chromosomal homologies between human and the Forrest's pika (Ochotona forresti, 2n = 54) by cross-species chromosome painting. Integration of our map with the published comparative chromosome map between human and rabbit has enabled the establishment of an indirect homology map between Forrest's pika and domestic rabbit (Oryctolagus cuniculus, 2n = 44), representing the 2 Lagomorpha families: Leporidae and Ochotonidae. Our results demonstrate that (1) most of the proposed ancestral eutherian syntenies or syntenic associations have been retained in the O. forresti genome; (2) the HSA1/10p association, one of the 2 signature rearrangements that were proposed to support the grouping of the orders Lagomorpha and Rodentia into a monophyletic clade called Glires, is also present in the O. forresti genome; and (3) Robertsonian translocations have contributed to the karyotype differences between O. forresti and O. cuniculus. |
| 收录类别 | SCI |
| 资助信息 | This study is supported partly by a grant from the National Nat- ural Science Foundation of China (No. 30770293) and MCB, SB RAS, RFBR grants (A.S.G.). F.Y. is supported by the Wellcome Trust. |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/9604]  |
| 专题 | 昆明动物研究所_保护遗传学(细胞库) 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming Yunnan 650223, China 2.College of Life Sciences, Shaoxing University, Shaoxing 3.College of Life Sciences, Ludong University, Yantai , PR China 4.Institute of Chemical Biology and Fundamental Medicine, Novosibirsk , Russia 5.Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton |
| 推荐引用方式 GB/T 7714 | Ye J[*],Nie WH,Graphodatsky AS,et al. Genome-Wide Comparative Chromosome Map between Human and the Forrest's Pika (Ochotona forresti) Established by Cross-Species Chromosome Painting: Further Support for the Glires Hypothesis[J]. CYTOGENETIC AND GENOME RESEARCH,2011,132(1-2):41-46. |
| APA | Ye J[*].,Nie WH.,Graphodatsky AS.,Yang F.,Wang J.,...&Jing M.(2011).Genome-Wide Comparative Chromosome Map between Human and the Forrest's Pika (Ochotona forresti) Established by Cross-Species Chromosome Painting: Further Support for the Glires Hypothesis.CYTOGENETIC AND GENOME RESEARCH,132(1-2),41-46. |
| MLA | Ye J[*],et al."Genome-Wide Comparative Chromosome Map between Human and the Forrest's Pika (Ochotona forresti) Established by Cross-Species Chromosome Painting: Further Support for the Glires Hypothesis".CYTOGENETIC AND GENOME RESEARCH 132.1-2(2011):41-46. |
入库方式： OAI收割
来源：昆明动物研究所
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