Molecular Cytogenetic Characterization of the Genome Organization of the 6-Banded Armadillo (Euphractus sexcinctus)
文献类型：期刊论文
| 作者 | Liu Y1; Ye J[*]1,2; Su W1; Yang F3; Nie W1; Fu B3; Ng BL3; Wang J1 |
| 刊名 | CYTOGENETIC AND GENOME RESEARCH
 |
| 出版日期 | 2011 |
| 卷号 | 132期号:1-2页码:31-40 |
| 关键词 | 6-Banded armadillo Ancestral Xenarthra karyotype Cloning Cross-species chromosome painting FISH mapping Repetitive DNAs Sequencing |
| 通讯作者 | yjpyyjjpp@hotmail.com |
| 合作状况 | 其它 |
| 英文摘要 | Xenarthra, as the probable earliest offshoot of the placental tree, represents a key taxon for understanding mammalian phylogeny. To gain further insight into the chromosomal evolution and genome organization of the xenarthrans, we have established the first genome-wide comparative chromosome map between human and the 6-banded armadillo (Euphractus sexcinctus, 2n = 58), a basal species on the Xenarthra branch, by reciprocal cross-species chromosome painting. In total, 22 human autosomal paints revealed 41 homologous segments in the euchromatic genome of E. sexcinctus. Our results provide further support for the notion that the 2 human homologous segmental associations, i.e. HSA 2/8 and 7a/10p, could constitute the synapomorphies that unite the xenarthrans. Moreover, we propose that the putative ancestral Xenarthra karyotype closely resemble the 2n = 54 karyotype of the E. sexcinctus, consisting of the equivalents of HSA1p, 1q, 2a, 2b, 2c/8c, 3/21, 4a, 4b/8b, 5, 6a, 6b, 7a/10p, 7b/16p, 8a, 9, 10q, 11, 12a/22a, 12b/22b, 13, 14/15, 16q/19q, 17, 18, 19p, 20, and X. In addition, we have analysed the C-banding patterns of E. sexcinctus, and cloned, FISH-mapped and sequenced 7 novel repetitive DNA segments, providing further information on the complexity of genome architecture of E. sexcinctus. |
| 收录类别 | SCI |
| 资助信息 | This study is supported partly by the grant from the National Natural Science Foundation of China (No. 30770293). B.F., B.L.N. and F.Y. are supported by the Well- come Trust (Grant No. WT077008). |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/9612]  |
| 专题 | 昆明动物研究所_保护遗传学(细胞库) 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, China 2.College of Life Sciences, Shaoxing University, Shaoxing , PR China 3.Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton , UK |
| 推荐引用方式 GB/T 7714 | Liu Y,Ye J[*],Su W,et al. Molecular Cytogenetic Characterization of the Genome Organization of the 6-Banded Armadillo (Euphractus sexcinctus)[J]. CYTOGENETIC AND GENOME RESEARCH,2011,132(1-2):31-40. |
| APA | Liu Y.,Ye J[*].,Su W.,Yang F.,Nie W.,...&Wang J.(2011).Molecular Cytogenetic Characterization of the Genome Organization of the 6-Banded Armadillo (Euphractus sexcinctus).CYTOGENETIC AND GENOME RESEARCH,132(1-2),31-40. |
| MLA | Liu Y,et al."Molecular Cytogenetic Characterization of the Genome Organization of the 6-Banded Armadillo (Euphractus sexcinctus)".CYTOGENETIC AND GENOME RESEARCH 132.1-2(2011):31-40. |
入库方式： OAI收割
来源：昆明动物研究所
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