Synthesis of a Class of Chiral-Bridged Phosphoramidite Ligands and Their Applications in the First Iridium-Catalyzed Asymmetric Addition of Arylboronic Acids to Isatins
文献类型：期刊论文
| 作者 | Zhuang, Yue1; He, Yuwei1; Zhou, Zihong1; Xia, Wang1; Cheng, Chuyu1; Wang, Meng1; Chen, Bin1; Zhou, Zhongyuan1; Pang, Jiyan1; Qiu, Liqin1 |
| 刊名 | JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2015 |
| 卷号 | 80期号:14页码:6968-6975 |
| 通讯作者 | qiuliqin@mail.sysu.edu.cn |
| 英文摘要 | A series of novel chiral phosphoramidite ligands based on chiral-bridged biphenyl backbones have been prepared conveniently and characterized. The ligands complexed with [IrCodCl](2) provided the first iridium catalyst system for the asymmetric addition of arylboronic acids to N-protected isatins with high efficiency. When performed in THF/H2O at 80 degrees C with 2 equiv of the arylboronic acids, the transformations acquired good to excellent results (up to 98% yield and 95% ee). |
| 学科主题 | Chemistry |
| 原文出处 | 0022-3263 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/14800]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 作者单位 | 1.[Zhuang, Yue 2.He, Yuwei 3.Zhou, Zihong 4.Xia, Wang 5.Cheng, Chuyu 6.Wang, Meng 7.Chen, Bin 8.Pang, Jiyan 9.Qiu, Liqin] Sun Yat Sen Univ, South China Sea Bioresource Exploitat & Utilizat, Key Lab Low Carbon Chem & Energy Conservat Guangd, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China 10.[Qiu, Liqin] Sun Yat Sen Univ, Huizhou Res Inst, Dayawan 516000, Huizhou, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhuang, Yue,He, Yuwei,Zhou, Zihong,et al. Synthesis of a Class of Chiral-Bridged Phosphoramidite Ligands and Their Applications in the First Iridium-Catalyzed Asymmetric Addition of Arylboronic Acids to Isatins[J]. JOURNAL OF ORGANIC CHEMISTRY,2015,80(14):6968-6975. |
| APA | Zhuang, Yue.,He, Yuwei.,Zhou, Zihong.,Xia, Wang.,Cheng, Chuyu.,...&Qiu, Liqin.(2015).Synthesis of a Class of Chiral-Bridged Phosphoramidite Ligands and Their Applications in the First Iridium-Catalyzed Asymmetric Addition of Arylboronic Acids to Isatins.JOURNAL OF ORGANIC CHEMISTRY,80(14),6968-6975. |
| MLA | Zhuang, Yue,et al."Synthesis of a Class of Chiral-Bridged Phosphoramidite Ligands and Their Applications in the First Iridium-Catalyzed Asymmetric Addition of Arylboronic Acids to Isatins".JOURNAL OF ORGANIC CHEMISTRY 80.14(2015):6968-6975. |
入库方式： OAI收割
来源：南海海洋研究所
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