Sesquiterpenoids and xanthones derivatives produced by sponge-derived fungus Stachybotry sp HH1 ZSDS1F1-2
文献类型：期刊论文
| 作者 | Qin, Chun1; Lin, Xiuping1; Lu, Xin1; Wan, Junting1; Zhou, Xuefeng1; Liao, Shengrong1; Tu, Zhengchao1; Xu, Shihai1; Liu, Yonghong1 |
| 刊名 | JOURNAL OF ANTIBIOTICS
 |
| 出版日期 | 2015 |
| 卷号 | 68期号:2页码:121-125 |
| 通讯作者 | tu_zhengchao@gibh.ac.cn ; txush@jnu.edu.cn ; yonghongliu@scsio.ac.cn |
| 英文摘要 | A new (2) and four known (1, 8-10) sesquiterpenoids, two new (3 and 4) and eight known (5-7, 11-15) xanthone derivatives were isolated from the cultures of sponge-derived fungus Stachybotry sp. HH1 ZDDS1F1-2. The structure of the compounds 1-15 was determined mainly by analysis of the one-dimensional and two-dimensional NMR spectroscopic data and by analogy with the data of those reported. Compound 1 was confirmed by X-ray crystallography. All the compounds were tested for their cytotoxic, antiinflammatory and antiviral (EV71) effects. Compounds 5, 7 and 11 showed significant cytotoxicity against selected human tumor cell lines. Compounds 3, 4 and 11 also displayed significant inhibitory activity against cycloooxygenase (COX-2). Compounds 4, 5 and 11 showed activities against intestinal virus EV71. |
| 学科主题 | Biotechnology & Applied Microbiology; Immunology; Microbiology; Pharmacology & Pharmacy |
| 原文出处 | 0021-8820 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/14868]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 作者单位 | 1.[Qin, Chun 2.Lin, Xiuping 3.Zhou, Xuefeng 4.Liao, Shengrong 5.Liu, Yonghong] Chinese Acad Sci, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, Guangzhou 510530, Guangdong, Peoples R China 6.[Qin, Chun 7.Xu, Shihai] Jinan Univ, Dept Chem, Guangzhou, Guangdong, Peoples R China 8.[Lu, Xin 9.Wan, Junting 10.Tu, Zhengchao] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou 510530, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qin, Chun,Lin, Xiuping,Lu, Xin,et al. Sesquiterpenoids and xanthones derivatives produced by sponge-derived fungus Stachybotry sp HH1 ZSDS1F1-2[J]. JOURNAL OF ANTIBIOTICS,2015,68(2):121-125. |
| APA | Qin, Chun.,Lin, Xiuping.,Lu, Xin.,Wan, Junting.,Zhou, Xuefeng.,...&Liu, Yonghong.(2015).Sesquiterpenoids and xanthones derivatives produced by sponge-derived fungus Stachybotry sp HH1 ZSDS1F1-2.JOURNAL OF ANTIBIOTICS,68(2),121-125. |
| MLA | Qin, Chun,et al."Sesquiterpenoids and xanthones derivatives produced by sponge-derived fungus Stachybotry sp HH1 ZSDS1F1-2".JOURNAL OF ANTIBIOTICS 68.2(2015):121-125. |
入库方式： OAI收割
来源：南海海洋研究所
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