Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungus Aspergillus westerdijkiae SCSIO 05233
文献类型:期刊论文
作者 | Fredimoses, Mangaladoss1; Zhou, Xuefeng1; Ai, Wen1; Tian, Xinpeng1; Yang, Bin1; Lin, Xiuping1; Xian, Jia-Yun1; Liu, Yonghong1 |
刊名 | NATURAL PRODUCT RESEARCH
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出版日期 | 2015 |
卷号 | 29期号:2页码:158-162 |
关键词 | deep sea Aspergillus westerdijkiae cytotoxicity antifouling |
通讯作者 | yonghongliu@scsio.ac.cn |
英文摘要 | A new methyl 2-(4-((2-hydroxy-3-methylbut-3-en-1-yl)oxy)phenyl) acetate 1, together with five known compounds 2-6, was isolated from the culture of the deep sea-derived fungus Aspergillus westerdijkiae SCSIO 05233. The new structure was determined by NMR (H-1 and C-13 NMR, HSQC, HMBC and MS) and optical rotation analysis. Compound 5 displayed weak inhibitory activities towards K562 and promyelocytic HL-60 with IC50 values of 25.8 and 44.9 mu M, and compound 6 showed strong antifouling activity with EC50 value 8.81 mu g/mL. |
学科主题 | Chemistry; Pharmacology & Pharmacy |
原文出处 | 1478-6419 |
源URL | [http://ir.scsio.ac.cn/handle/344004/14881] ![]() |
专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
作者单位 | 1.[Fredimoses, Mangaladoss 2.Zhou, Xuefeng 3.Ai, Wen 4.Tian, Xinpeng 5.Yang, Bin 6.Lin, Xiuping 7.Xian, Jia-Yun 8.Liu, Yonghong] Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Guangdong, Peoples R China |
推荐引用方式 GB/T 7714 | Fredimoses, Mangaladoss,Zhou, Xuefeng,Ai, Wen,et al. Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungus Aspergillus westerdijkiae SCSIO 05233[J]. NATURAL PRODUCT RESEARCH,2015,29(2):158-162. |
APA | Fredimoses, Mangaladoss.,Zhou, Xuefeng.,Ai, Wen.,Tian, Xinpeng.,Yang, Bin.,...&Liu, Yonghong.(2015).Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungus Aspergillus westerdijkiae SCSIO 05233.NATURAL PRODUCT RESEARCH,29(2),158-162. |
MLA | Fredimoses, Mangaladoss,et al."Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungus Aspergillus westerdijkiae SCSIO 05233".NATURAL PRODUCT RESEARCH 29.2(2015):158-162. |
入库方式: OAI收割
来源:南海海洋研究所
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