Chrysamides A-C, Three Dimeric Nitrophenyl trans-Epoxyamides Produced by the Deep-Sea-Derived Fungus Penicillium chrysogenum SCSIO41001
文献类型：期刊论文
| 作者 | Chen, Shengtian; Wang, Junfeng; Lin, Xiuping; Zhao, Bingxin; Wei, Xiaoyi; Li, Guangqiang; Kaliaperumal, Kumaravel; Liao, Shengrong; Yang, Bin; Zhou, Xuefeng |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2016 |
| 卷号 | 18期号:15页码:3650-3653 |
| 通讯作者 | Liu, YH (reprint author), Chinese Acad Sci, South China Sea Inst Oceanol, RNAM Ctr Marine Microbiol, Guangdong Key Lab Marine Matria Med,CAS Key Lab T, Guangzhou 510301, Guangdong, Peoples R China. ; Xu, SH (reprint author), Jinan Univ, Dept Chem, Guangzhou 510632, Guangdong, Peoples R China. |
| 英文摘要 | Three dimeric nitrophenyl trans-epoxyamides, chrysamides A-C (1-3), were obtained from the deep-sea-derived fungus Penicillium chrysogenum SCSIO41001. Their structures were characterized by spectroscopic analysis, electronic circular dichroism computations, and X-ray single-crystal diffraction analysis. Notably, compound 1 possesses a novel centrosymmetric dimer skeleton featuring an unprecedented 7-oxa-2,5-diazabicyclo[2.2.1]heptane ring system, which represents the first example of dimeric nitrophenyl trans-epoxyamide in nature. Compound 3 suppresses the production of proinflammatory cytokine interleukin-17. A possible biosynthetic pathway of 1-3 was proposed. |
| 学科主题 | Chemistry |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/15306]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | Chen, Shengtian,Wang, Junfeng,Lin, Xiuping,et al. Chrysamides A-C, Three Dimeric Nitrophenyl trans-Epoxyamides Produced by the Deep-Sea-Derived Fungus Penicillium chrysogenum SCSIO41001[J]. ORGANIC LETTERS,2016,18(15):3650-3653. |
| APA | Chen, Shengtian.,Wang, Junfeng.,Lin, Xiuping.,Zhao, Bingxin.,Wei, Xiaoyi.,...&Liu, Yonghong.(2016).Chrysamides A-C, Three Dimeric Nitrophenyl trans-Epoxyamides Produced by the Deep-Sea-Derived Fungus Penicillium chrysogenum SCSIO41001.ORGANIC LETTERS,18(15),3650-3653. |
| MLA | Chen, Shengtian,et al."Chrysamides A-C, Three Dimeric Nitrophenyl trans-Epoxyamides Produced by the Deep-Sea-Derived Fungus Penicillium chrysogenum SCSIO41001".ORGANIC LETTERS 18.15(2016):3650-3653. |
入库方式： OAI收割
来源：南海海洋研究所
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