New phenyl derivatives from endophytic fungus Botryosphaeria sp SCSIO KcF6 derived of mangrove plant Kandelia candel
文献类型：期刊论文
| 作者 | Ju, Zhi-ran; Qin, Xiaochu; Lin, Xiu-ping; Wang, Jun-feng; Kaliyaperumal, Kumaravel; Tian, Yong-qi; Liu, Juan; Liu, Fen; Tu, Zhengchao; Xu, Shi-hai |
| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2016 |
| 卷号 | 30期号:2页码:192-198 |
| 关键词 | endophytic fungus Botryosphaeria sp SCSIO KcF6 COX-2 inhibitory activity |
| 通讯作者 | Tu, ZC (reprint author), Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Lab Mol Engn, Guangzhou 510530, Guangdong, Peoples R China. |
| 中文摘要 | Two new phenyl derivatives (1 and 3), along with two new natural products (4 and 5), and three known compounds (2, 6 and 7), were isolated from an endophytic fungus Botryosphaeria sp. SCSIO KcF6. The structures of these compounds 1-7 were elucidated by the extensive 1D and 2D-NMR and HRESIMS Data analysis, and compared with those of reported data. The absolute configuration of the compounds 1 and 3 were assigned by optical rotation and CD data. The isolated compounds were evaluated for their cytotoxic, anti-inflammatory (COX-2) and antimicrobial activities. Compound 3 exhibited a specific COX-2 inhibitory activity with the IC50 value of 1.12M. |
| 学科主题 | Chemistry; Pharmacology & Pharmacy |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/15509]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | Ju, Zhi-ran,Qin, Xiaochu,Lin, Xiu-ping,et al. New phenyl derivatives from endophytic fungus Botryosphaeria sp SCSIO KcF6 derived of mangrove plant Kandelia candel[J]. NATURAL PRODUCT RESEARCH,2016,30(2):192-198. |
| APA | Ju, Zhi-ran.,Qin, Xiaochu.,Lin, Xiu-ping.,Wang, Jun-feng.,Kaliyaperumal, Kumaravel.,...&Liu, Yonghong.(2016).New phenyl derivatives from endophytic fungus Botryosphaeria sp SCSIO KcF6 derived of mangrove plant Kandelia candel.NATURAL PRODUCT RESEARCH,30(2),192-198. |
| MLA | Ju, Zhi-ran,et al."New phenyl derivatives from endophytic fungus Botryosphaeria sp SCSIO KcF6 derived of mangrove plant Kandelia candel".NATURAL PRODUCT RESEARCH 30.2(2016):192-198. |
入库方式： OAI收割
来源：南海海洋研究所
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