A New Diketopiperazine from the Marine Sponge Callyspongia Species
文献类型：期刊论文
| 作者 | Yang, Bin; Huang, Jingxia; Lin, Xiuping; Zhang, Yanying; Tao, Huaming; Liu, Yonghong |
| 刊名 | RECORDS OF NATURAL PRODUCTS
 |
| 出版日期 | 2016 |
| 卷号 | 10期号:1页码:117-121 |
| 关键词 | Callyspongia sp. Diketopiperazine Chemical constituents Antifouling activity |
| 通讯作者 | Liu, YH (reprint author), Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med,Res Ctr Marine M, Guangzhou 510301, Guangdong, Peoples R China. |
| 中文摘要 | Chemical investigation of the sponge Callyspongia sp. from the South China Sea afforded one new diketopiperazine, cyclo-(R-Pro-6-hydroxyl-S-Ile) (1), along with six known diketopiperazines: staphyloamide A (2), cyclo-(S-Pro-S-Phe) (3), cyclo-(R-Pro-R-Phe) (4), cyclo-(S-Pro-R-Leu) (5), cyclo-(S-Pro-R-Ala) (6), cyclo( R-Tyr-R-Phe) (7), and three known tryptophan-derived alkaloids: C-2-alpha-D-mannosylpyranosyl-tryptophan (8), (1R, 3S)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid (9), and (1R, 3R)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b] indole-3-carboxylic acid (10). The structures were determined on the basis of NMR and MS analysis, and the absolute configuration was determined by comparison of the optical rotation with the known compounds. This is the first report of compounds 1, 2, 8-10 from the sponge Callyspongia. Cyclo-(S-Pro-R-Leu) (5), and cyclo-(S-Pro-R-Ala) (6) exhibited antifouling activity against cyprid larvae of the barnacle with the LC50 values of 3.5 mu g/cm(2) and 6.0 mu g/cm(2), respectively. |
| 学科主题 | Plant Sciences; Chemistry; Pharmacology & Pharmacy |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/15528]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | Yang, Bin,Huang, Jingxia,Lin, Xiuping,et al. A New Diketopiperazine from the Marine Sponge Callyspongia Species[J]. RECORDS OF NATURAL PRODUCTS,2016,10(1):117-121. |
| APA | Yang, Bin,Huang, Jingxia,Lin, Xiuping,Zhang, Yanying,Tao, Huaming,&Liu, Yonghong.(2016).A New Diketopiperazine from the Marine Sponge Callyspongia Species.RECORDS OF NATURAL PRODUCTS,10(1),117-121. |
| MLA | Yang, Bin,et al."A New Diketopiperazine from the Marine Sponge Callyspongia Species".RECORDS OF NATURAL PRODUCTS 10.1(2016):117-121. |
入库方式： OAI收割
来源：南海海洋研究所
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