Asteltoxins with Antiviral Activities from the Marine Sponge-Derived Fungus Aspergillus sp SCSIO XWS02F40
文献类型：期刊论文
| 作者 | Tian, Yong-Qi; Lin, Xiu-Ping; Wang, Zhen; Zhou, Xue-Feng; Qin, Xiao-Chu; Kaliyaperumal, Kumaravel; Zhang, Tian-Yu; Tu, Zheng-Chao; Liu, Yonghong |
| 刊名 | MOLECULES
 |
| 出版日期 | 2016 |
| 卷号 | 21期号:1页码:- |
| 关键词 | sponge-derived fungus asteltoxins antiviral (H1N1 and H3N2) activity |
| 通讯作者 | Liu, YH (reprint author), Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med,RNAM Ctr Marine, Guangzhou 510301, Guangdong, Peoples R China. |
| 中文摘要 | Two new asteltoxins named asteltoxin E (2) and F (3), and a new chromone (4), together with four known compounds were isolated from a marine sponge-derived fungus, Aspergillus sp. SCSIO XWS02F40. The structures of the compounds (1-7) were determined by the extensive 1D- and 2D-NMR spectra, and HRESIMS spectrometry. All the compounds were tested for their antiviral (H1N1 and H3N2) activity. Compounds 2 and 3 showed significant activity against H3N2 with the prominent IC50 values of 6.2 +/- 0.08 and 8.9 +/- 0.3 M, respectively. In addition, compound 2 also exhibited inhibitory activity against H1N1 with an IC50 value of 3.5 +/- 1.3 M. |
| 学科主题 | Chemistry |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/15530]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | Tian, Yong-Qi,Lin, Xiu-Ping,Wang, Zhen,et al. Asteltoxins with Antiviral Activities from the Marine Sponge-Derived Fungus Aspergillus sp SCSIO XWS02F40[J]. MOLECULES,2016,21(1):-. |
| APA | Tian, Yong-Qi.,Lin, Xiu-Ping.,Wang, Zhen.,Zhou, Xue-Feng.,Qin, Xiao-Chu.,...&Liu, Yonghong.(2016).Asteltoxins with Antiviral Activities from the Marine Sponge-Derived Fungus Aspergillus sp SCSIO XWS02F40.MOLECULES,21(1),-. |
| MLA | Tian, Yong-Qi,et al."Asteltoxins with Antiviral Activities from the Marine Sponge-Derived Fungus Aspergillus sp SCSIO XWS02F40".MOLECULES 21.1(2016):-. |
入库方式： OAI收割
来源：南海海洋研究所
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