Novel transmission element of antibiotic resistance genes ISCR and its ecological risk
文献类型：期刊论文
| 作者 | Chen, Lin-Lin ; Li, Bao-Quan
|
| 刊名 | Chinese Journal of Applied Ecology
 |
| 出版日期 | 2015-10-01 |
| 卷号 | 26期号:10页码:3215-3225 |
| 关键词 | antibiotic resistance ecological impact future prospect gene flow genetic analysis horizontal transmission research work risk assessment Bacteria (microorganisms) |
| ISSN号 | 1001-9332 |
| 其他题名 | 新型抗生素抗性基因传播元件ISCR及其生态风险 |
| 产权排序 | (1) Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai; Shandong, China |
| 通讯作者 | Li, Bao-Quan (bqli@yic.ac.cn) |
| 英文摘要 | Antibiotic resistance genes (ARGs) as emerging environmental pollutants have become the focus of attention of many disciplines. The transmission and dissemination of ARGs in various environmental media has great hazards to environment and poses serious threat to human health. ISCR (insertion sequence common regions) elements are newly discovered resistance genes transmission elements. Because of the special genetic structure, ISCR elements can move any adjacent DNA sequences by rolling-circle replication and homologous recombination, and have become the efficient transmission elements of ARGs among different DNA molecules or bacterial species. Around the world, 27 members of the ISCR family have been discovered up to now. A lot of circumstantial evidence has indicated that ISCR elements may be associated with the mobility and transmission of kinds of ARGs, especially multiple drug resistance genes (MDR). In this review, we described some aspects of ISCR elements, including the horizontal transfer of ARGs, structural characteristics of ISCRs, classification of ISCRs and their related ARGs, research methods of these elements, possible ecological risk of ISCRs and proposal of research directions, hoping to provide help for further related research in the future. ©, 2015, Editorial Board of Chinese Journal of Applied Ecology. All right reserved. |
| 研究领域[WOS] | Population Genetics |
| 收录类别 | CSCD |
| 语种 | 中文 |
| 源URL | [http://ir.yic.ac.cn/handle/133337/17495]  |
| 专题 | 烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室 |
| 作者单位 | Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences |
| 推荐引用方式 GB/T 7714 | Chen, Lin-Lin,Li, Bao-Quan. Novel transmission element of antibiotic resistance genes ISCR and its ecological risk[J]. Chinese Journal of Applied Ecology,2015,26(10):3215-3225. |
| APA | Chen, Lin-Lin,&Li, Bao-Quan.(2015).Novel transmission element of antibiotic resistance genes ISCR and its ecological risk.Chinese Journal of Applied Ecology,26(10),3215-3225. |
| MLA | Chen, Lin-Lin,et al."Novel transmission element of antibiotic resistance genes ISCR and its ecological risk".Chinese Journal of Applied Ecology 26.10(2015):3215-3225. |
入库方式： OAI收割
来源：烟台海岸带研究所
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