Design, synthesis of novel starch derivative bearing 1,2,3-triazolium and pyridinium and evaluation of its antifungal activity
文献类型：期刊论文
| 作者 | Tan, Wenqiang ; Li, Qing; Gao, Zhenpeng; Qiu, Shuai; Dong, Fang; Guo, Zhanyong
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| 刊名 | CARBOHYDRATE POLYMERS
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| 出版日期 | 2017-02-10 |
| 卷号 | 157页码:236-243 |
| 关键词 | Starch derivative Antifungal activity 1,2,3-Triazolium Pyridinium Click chemistry |
| ISSN号 | 0144-8617 |
| 产权排序 | [Tan, Wenqiang; Li, Qing; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Tan, Wenqiang] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Gao, Zhenpeng] Harbin Inst Technol Weihai, Sch Marine Sci & Technol, Weihai 264209, Peoples R China; [Qiu, Shuai] Yantai Univ, Coll Life Sci, Yantai 264005, Peoples R China |
| 通讯作者 | Guo, ZY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China. zhanyongguo@hotmail.com |
| 英文摘要 | Based on cuprous-catalyzed azide-alkyne cycloaddition (CuAAC), starch derivative bearing 1,2,3-triazole and pyridine (II) was prepared and subsequently followed by alkylation with iodomethane to synthesize starch derivative bearing 1,2,3-triazolium and pyridinium (III). The antifungal activities of starch derivatives against Colletotrichum lagenarium, Watermelon fusarium, and Phomopsis asparagi, were then assayed by hypha measurement in vitro. Apparently, starch derivatives showed enhanced antifungal activity against three fungi at the tested concentrations compared with starch. Especially, the best inhibitory index of starch derivative (III) against Colletotrichum lagenarium attained 97% above at 1.0 mg/mL. Meanwhile, starch derivative (III) had stronger antifungal activity than starch derivative (II), which was reasonable to propose that the alkylation of 1,2,3-triazole and pyridine was significant for enhanced antifungal activity. As this novel starch derivative bearing 1,2,3-triazolium and pyridinium could be prepared efficiently and exhibited superduper antifungal activity, this material might provide an effective way and notion to prepare novel antifungal agents. (C) 2016 Elsevier Ltd. All rights reserved. |
| 研究领域[WOS] | Chemistry ; Polymer Science |
| 关键词[WOS] | QUATERNARY AMMONIUM CHITOSAN ; CLICK CHEMISTRY ; ANTIBACTERIAL ACTIVITY ; STRUCTURAL-PROPERTIES ; IONIC LIQUID)S ; POLYADDITION ; CATALYST |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000391896800027 |
| 源URL | [http://ir.yic.ac.cn/handle/133337/17512]  |
| 专题 | 烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室 烟台海岸带研究所_污染过程与控制实验室 海岸带生物资源高效利用研究与发展中心 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Harbin Inst Technol Weihai, Sch Marine Sci & Technol, Weihai 264209, Peoples R China 5.Yantai Univ, Coll Life Sci, Yantai 264005, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tan, Wenqiang,Li, Qing,Gao, Zhenpeng,et al. Design, synthesis of novel starch derivative bearing 1,2,3-triazolium and pyridinium and evaluation of its antifungal activity[J]. CARBOHYDRATE POLYMERS,2017,157:236-243. |
| APA | Tan, Wenqiang,Li, Qing,Gao, Zhenpeng,Qiu, Shuai,Dong, Fang,&Guo, Zhanyong.(2017).Design, synthesis of novel starch derivative bearing 1,2,3-triazolium and pyridinium and evaluation of its antifungal activity.CARBOHYDRATE POLYMERS,157,236-243. |
| MLA | Tan, Wenqiang,et al."Design, synthesis of novel starch derivative bearing 1,2,3-triazolium and pyridinium and evaluation of its antifungal activity".CARBOHYDRATE POLYMERS 157(2017):236-243. |
入库方式： OAI收割
来源：烟台海岸带研究所
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