A Three-Dimensional Origami Paper-Based Device for Potentiometric Biosensing
文献类型：期刊论文
| 作者 | Ding, JW ; Li, BW; Chen, LX; Qin, W
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| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
 |
| 出版日期 | 2016-10-10 |
| 卷号 | 55期号:42页码:13033-13037 |
| 关键词 | biosensors enzyme-based assays origami paper-based devices potentiometry |
| ISSN号 | 1433-7851 |
| 产权排序 | [Ding, Jiawang; Li, Bowei; Chen, Lingxin; Qin, Wei] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Shandong, Peoples R China; [Ding, Jiawang; Li, Bowei; Chen, Lingxin; Qin, Wei] YICCAS, Shandong Prov Key Lab Coastal Environm Proc, Yantai 264003, Shandong, Peoples R China |
| 通讯作者 | Qin, W (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Shandong, Peoples R China. ; Qin, W (reprint author), YICCAS, Shandong Prov Key Lab Coastal Environm Proc, Yantai 264003, Shandong, Peoples R China. Email:wqin@yic.ac.cn |
| 英文摘要 | Current paper-based potentiometric ion-sensing platforms are planar devices used for clinically relevant ions. These devices, however, have not been designed for the potentiometric biosensing of proteins or small molecule analytes. A three-dimensional origami paper-based device, in which a solid-contact ion-selective electrode is integrated with an all-solid-state reference electrode, is described for the first time. The device is made by impregnation of paper with appropriate bioreceptors and reporting reagents on different zones. By folding and unfolding the paper structures, versatile potentiometric bioassays can be performed. A USB-controlled miniaturized electrochemical detector can be used for simple and in situ measurements. Using butyrylcholinesterase as a model enzyme, the device has been successfully applied to the detection of enzyme activities and organophosphate pesticides involved in the enzymatic system as inhibitors. The proposed 3D origami paper device allows the potentiometric biosensing of proteins and small molecules in a simple, portable, and cost-effective way. |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | ION-SELECTIVE ELECTRODES ; SOLID-CONTACT ; ELECTROANALYTICAL DEVICES ; ELECTROCHEMICAL DETECTION ; MICROFLUIDIC DEVICES ; MEMBRANE ELECTRODES ; CARBON NANOTUBES ; DETECTION LIMITS ; SENSORS ; PLATFORM |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000385799200013 |
| 源URL | [http://ir.yic.ac.cn/handle/133337/17468]  |
| 专题 | 烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室 |
| 推荐引用方式 GB/T 7714 | Ding, JW,Li, BW,Chen, LX,et al. A Three-Dimensional Origami Paper-Based Device for Potentiometric Biosensing[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2016,55(42):13033-13037. |
| APA | Ding, JW,Li, BW,Chen, LX,&Qin, W.(2016).A Three-Dimensional Origami Paper-Based Device for Potentiometric Biosensing.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,55(42),13033-13037. |
| MLA | Ding, JW,et al."A Three-Dimensional Origami Paper-Based Device for Potentiometric Biosensing".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 55.42(2016):13033-13037. |
入库方式： OAI收割
来源：烟台海岸带研究所
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