Brain-wide map of projections from mice ventral subiculum
文献类型：期刊论文
| 作者 | Tang, He1,2; Wu, Gui-Sheng1; Xie, Jing1,2; He, Xiaobin3; Deng, Ke1; Wang, Huadong3; Xu, Fuqiang3,4; Luo, Huai-Rong1 |
| 刊名 | NEUROSCIENCE LETTERS
 |
| 出版日期 | 2016-08-26 |
| 卷号 | 629页码:171-179 |
| 关键词 | Hippocampal formation Ventral subiculum Herpes simplex virus Neural circuits Brain map |
| 英文摘要 | The hippocampal formation plays a critical role in episodic memory formation and spatial navigation. Within the hippocampus, the subiculum is considered to be a hub connecting the hippocampal formation to the remainder of the brain. There are functional differences between the dorsal and ventral part of subiculum, while the ventral subiculum (vSub) plays a role in anxiety, stress and emotion. In the present study, we examined the projection of the ventral subiculum to the whole brain in mice by using a modified herpes simplex virus 1 strain H129 with an inserted fluorescent protein gene. In our experiments, the modified H129 transits the primary-order, second-order, and third-order neuronal projections at 36-44, 52-60 and 68-76 h after inoculation in mice, respectively. Our data revealed that vSub directly projects to the medial entorhinal cortex, amygdalohippocampal area, anterodorsal thalamic nucleus, medial hypothalamus, supramammillary nucleus, medial septal nucleus and adjacent diagonal band, the connections between median raphe nucleus and interpeduncular nucleus in brain stem, while ventral prefrontal cortex, laterodorsal tegmental nucleus and locus coeruleus receives second-order projections from vSub. Our data would help further understanding the functional connections of vSub with other brain regions. (C) 2016 Elsevier Ireland Ltd. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Neurosciences |
| 研究领域[WOS] | Neurosciences & Neurology |
| 关键词[WOS] | PHASEOLUS-VULGARIS-LEUKOAGGLUTININ ; TOPOGRAPHICAL ORGANIZATION ; ENTORHINAL CORTEX ; HIPPOCAMPAL CA1 ; RAT ; CONNECTIONS ; NEURONS ; PATTERNS ; HYPOTHALAMUS ; MORPHOLOGY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000382409000031 |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/9583]  |
| 专题 | 武汉物理与数学研究所_磁共振应用研究部 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 134 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 3.Chinese Acad Sci, Wuhan Inst Phys & Math, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan 430071, Peoples R China 4.Wuhan Natl Lab Optoelect, Wuhan 430074, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tang, He,Wu, Gui-Sheng,Xie, Jing,et al. Brain-wide map of projections from mice ventral subiculum[J]. NEUROSCIENCE LETTERS,2016,629:171-179. |
| APA | Tang, He.,Wu, Gui-Sheng.,Xie, Jing.,He, Xiaobin.,Deng, Ke.,...&Luo, Huai-Rong.(2016).Brain-wide map of projections from mice ventral subiculum.NEUROSCIENCE LETTERS,629,171-179. |
| MLA | Tang, He,et al."Brain-wide map of projections from mice ventral subiculum".NEUROSCIENCE LETTERS 629(2016):171-179. |
入库方式： OAI收割
来源：武汉物理与数学研究所
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