A new isocoumarin from the aerial parts of Aconitum gymnandrum
文献类型：期刊论文
| 作者 | Zhao, Jian-Qiang1,2,5; Wang, Yan-Ming3,4,5; Wang, Shuo1,2; Dang, Jun1,2; Shi, Yan-Ping3,4; Mei, Li-Juan1,2; Tao, Yan-Duo1,2 |
| 刊名 | natural product research
 |
| 出版日期 | 2016 |
| 卷号 | 30期号:15页码:1746-1752 |
| 关键词 | Aconitum gymnandrum isocourmain cytotoxic activity |
| 英文摘要 | a new isocoumarin, along with 10 known compounds, was isolated from the aerial parts of aconitum gymnandrum. their structures were elucidated by spectroscopic methods including extensive 1d and 2d nmr techniques. among the known compounds, compound 11 was obtained as a natural product for the first time, which was previously reported as a synthetic product. in addition, compounds 1-5, 7 and 9 were tested for their cytotoxicity against four human cancer cell lines. the results showed that compounds 3, 4 and 7 displayed cytotoxicity against lung cancer a549 and gastric cancer mgc80, respectively, whereas 5 and 9 showed selective cytotoxicity against hepatocellular carcinoma hepg2. |
| WOS标题词 | science & technology ; physical sciences ; life sciences & biomedicine |
| 类目[WOS] | chemistry, applied ; chemistry, medicinal |
| 研究领域[WOS] | chemistry ; pharmacology & pharmacy |
| 关键词[WOS] | qinghai-tibetan plateau ; agrimonia-pilosa ; alkaloids |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000382561200011 |
| 源URL | [http://ir.nwipb.ac.cn/handle/363003/6433]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 作者单位 | 1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res CAS, Xinning, Peoples R China 2.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Qinghai Prov, Xinning, Peoples R China 3.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources CAS, Lanzhou, Peoples R China 4.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou, Peoples R China 5.Univ Chinese Acad Sci, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Jian-Qiang,Wang, Yan-Ming,Wang, Shuo,et al. A new isocoumarin from the aerial parts of Aconitum gymnandrum[J]. natural product research,2016,30(15):1746-1752. |
| APA | Zhao, Jian-Qiang.,Wang, Yan-Ming.,Wang, Shuo.,Dang, Jun.,Shi, Yan-Ping.,...&Tao, Yan-Duo.(2016).A new isocoumarin from the aerial parts of Aconitum gymnandrum.natural product research,30(15),1746-1752. |
| MLA | Zhao, Jian-Qiang,et al."A new isocoumarin from the aerial parts of Aconitum gymnandrum".natural product research 30.15(2016):1746-1752. |
入库方式： OAI收割
来源：西北高原生物研究所
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