Meroterpenoids and a Naphthoquinone from Arnebia euchroma and Their Cytotoxic Activity
文献类型：期刊论文
| 作者 | Wang, Lun; Li, Fu; Liu, Xin; Chen, Bin; Yu, Kai; Wang, Ming-Kui |
| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2015 |
| 卷号 | 81期号:4页码:320-326 |
| 关键词 | NATURALLY-OCCURRING QUINONES LITHOSPERMUM-ERYTHRORHIZON CLAVILACTONES DERIVATIVES INHIBITORS CORDIA AGENTS |
| 产权排序 | 1 |
| 通讯作者 | Wang, MK (reprint author), Chinese Acad Sci, Chengdu Inst Biol, 9,Sect 4,Renmin South Rd, Chengdu 610041, Peoples R China. |
| 合作状况 | 国内 |
| 英文摘要 | Four new meroterpenoids, arnebinols A-D (1-4), and one new prenylated naphthoquinone, 5,8-O-dimethyl-11-deoxyalkannin (5), together with seven known meroterpenoids (6-12) were isolated from the roots of Arnebia euchroma. The structures of the isolated compounds were elucidated unambiguously by spectroscopic data analysis, as well as X-ray-single crystal diffraction analysis. Arnebinol A (1) and B (2) are rare meroterpenoids possessing a 6/10/5 tricyclic ring system. Compounds 1-12 were evaluated for their cytotoxicities against MG-63 and SNU387 human cancer cell lines. Compound 5 exhibited the most potent activity with IC50 values of 2.69 mu M and 6.08 mu M, respectively. |
| 学科主题 | Plant Sciences; Pharmacology & Pharmacy |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://210.75.237.14/handle/351003/27597]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Wang, Lun,Li, Fu,Liu, Xin,et al. Meroterpenoids and a Naphthoquinone from Arnebia euchroma and Their Cytotoxic Activity[J]. PLANTA MEDICA,2015,81(4):320-326. |
| APA | Wang, Lun,Li, Fu,Liu, Xin,Chen, Bin,Yu, Kai,&Wang, Ming-Kui.(2015).Meroterpenoids and a Naphthoquinone from Arnebia euchroma and Their Cytotoxic Activity.PLANTA MEDICA,81(4),320-326. |
| MLA | Wang, Lun,et al."Meroterpenoids and a Naphthoquinone from Arnebia euchroma and Their Cytotoxic Activity".PLANTA MEDICA 81.4(2015):320-326. |
入库方式： OAI收割
来源：成都生物研究所
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