The neural transfer effect of working memory training to enhance hedonic processing in individuals with social anhedonia
文献类型：期刊论文
| 作者 | Li, Xu1,2,3 ; Li, Zhi1,2; Li, Ke4; Zeng, Ya-wei4; Shi, Hai-song1,2,5; Xie, Wen-lan1,2; Yang, Zhuo-ya1,2; Lui, Simon S. Y.1,2,6; Cheung, Eric F. C.6; Leung, Ada W. S.7,8
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| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2016-10-18 |
| 卷号 | 6期号:0页码:1-10 |
| 通讯作者邮箱 | rckchan@psych.ac.cn |
| ISSN号 | 2045-2322 |
| 通讯作者 | Chan, Raymond C. K. |
| 英文摘要 | Anhedonia, the diminished ability to experience pleasure, is a challenging negative symptom in patients with schizophrenia and can be observed in at-risk individuals with schizotypy. Deficits in hedonic processing have been postulated to be related to decreased motivation to engage in potentially rewarding events. It remains unclear whether non-pharmacological interventions, such as cognitive training, could improve anhedonia. The present study aimed to examine the neural mechanism for alleviating hedonic deficits with working memory ( WM) training in individuals with social anhedonia. Fifteen individuals with social anhedonia were recruited and received 20 sessions of training on a dual n-back task, five sessions a week. Functional imaging paradigms of the Monetary Incentive Delay ( MID) and the Affective Incentive Delay ( AID) tasks were administered both before and after the training to evaluate the neural transfer effects on hedonic processing ability. Enhanced brain activations related to anticipation were observed at the anterior cingulate cortex, the left dorsal striatum and the left precuneus with the AID task, and at the dorsolateral prefrontal cortex and the supramarginal gyrus with the MID task. The present findings support that WM training may improve monetary-based and affective-based hedonic processing in individuals with social anhedonia. |
| WOS标题词 | Science & Technology |
| 类目[WOS] | Multidisciplinary Sciences |
| 研究领域[WOS] | Science & Technology - Other Topics |
| 关键词[WOS] | COGNITIVE REMEDIATION THERAPY ; EMOTIONAL EXPRESSIVITY SCALE ; MAJOR DEPRESSIVE DISORDER ; NUCLEUS-ACCUMBENS ; SCHIZOPHRENIA ; BRAIN ; FMRI ; METAANALYSIS ; MONETARY ; REWARDS |
| 收录类别 | SCI ; SSCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000385586900001 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/20690]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 作者单位 | 1.Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, CAS Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100048, Peoples R China 3.Cent China Normal Univ, Sch Psychol, Key Lab Adolescent Cyberpsychol & Behav CCNU, Minist Educ, Wuhan 430079, Peoples R China 4.Hosp 306, MRI Ctr, Beijing 100101, Peoples R China 5.North China Elect Power Univ, Beijing 102206, Peoples R China 6.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China 7.Univ Alberta, Dept Occupat Therapy, Edmonton, AB T6G 2G4, Canada 8.Univ Alberta, Inst Neurosci & Mental Hlth, Edmonton, AB T6G 2G4, Canada |
| 推荐引用方式 GB/T 7714 | Li, Xu,Li, Zhi,Li, Ke,et al. The neural transfer effect of working memory training to enhance hedonic processing in individuals with social anhedonia[J]. SCIENTIFIC REPORTS,2016,6(0):1-10. |
| APA | Li, Xu.,Li, Zhi.,Li, Ke.,Zeng, Ya-wei.,Shi, Hai-song.,...&Chan, Raymond C. K..(2016).The neural transfer effect of working memory training to enhance hedonic processing in individuals with social anhedonia.SCIENTIFIC REPORTS,6(0),1-10. |
| MLA | Li, Xu,et al."The neural transfer effect of working memory training to enhance hedonic processing in individuals with social anhedonia".SCIENTIFIC REPORTS 6.0(2016):1-10. |
入库方式： OAI收割
来源：心理研究所
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