Magnetic carbon nitride nanocomposites as enhanced peroxidase mimetics for use in colorimetric bioassays, and their application to the determination of H2O2 and glucose
文献类型:期刊论文
作者 | Chen J(陈佳)1![]() ![]() ![]() |
刊名 | Microchimica Acta
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出版日期 | 2016 |
卷号 | 183期号:12页码:3191-3199 |
关键词 | Magnetic nanocomposites Enzyme mimetic Hydrogen peroxide Glucose Transmission electron microscopy X-ray diffractionFourier transform infrared spectroscopy X-ray photoelectron spectra Magnetization hysteresis loops |
ISSN号 | 0026-3672 |
通讯作者 | 邱洪灯 |
英文摘要 | Graphite-like carbon nitride − Fe3O4 magnetic nanocomposites were synthesized by a chemical co-precipitation method. The nanocomposites were characterized by transmission electron microscopy, X-ray diffraction, FTIR spectroscopy, X-ray photoelectron spectroscopy and magnetization hysteresis loops. The nanocomposites exhibit enhanced peroxidase-like activity (compared to that of graphite-like carbon nitride or Fe3O4 NPs). More specifically, they are capable of catalyzing the oxidation of different peroxidase substrates (such as TMB, ABTS or OPD) by H2O2 to produce the typical color reactions (blue, green or orange). The nanocomposites retain their magnetic properties and can be separated by an external magnet. On the basis of these findings, a highly sensitive and selective method was applied to the determination of H2O2 and glucose (by using glucose oxidase). It was successfully applied to the determination of glucose in (spiked) human serum. Compared to other nanomaterial-based peroxidase mimetics, the one described here provides distinctly higher sensitivity for both H2O2 and glucose, with detection limits as low as 0.3 μM and 0.25 μM, respectively. |
学科主题 | 分析化学与药物化学 |
收录类别 | SCI |
资助信息 | the National Natural Science Foundation of China (no. 21405163);the Foundation for Sci&Tech Research Project of Gansu Province (No. 145RJYA271);the Funds for Distinguished Young Scientists of Gansu (1506RJDA281);the top priority program of “One-Three-Five” Strategic Planning of Lanzhou Institute of Chemical Physics, CAS |
语种 | 英语 |
WOS记录号 | WOS:000389194500013 |
源URL | [http://210.77.64.217/handle/362003/20913] ![]() |
专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 兰州化学物理研究所_OSSO国家重点实验室 |
通讯作者 | Qiu HD(邱洪灯) |
作者单位 | 1.Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu ProvinceLanzhou Institute of Chemical Physics, Chinese Academy of Sciences Lanzhou China 2.School of Materials Science and Engineering, Key Laboratory for Advanced Technologies of Materials of the Ministry of Education Southwest Jiaotong University Chengdu China 3.State Key Laboratory for Oxo Synthesis and Selective OxidationLanzhou Institute of Chemical Physics, Chinese Academy of Sciences Lanzhou China |
推荐引用方式 GB/T 7714 | Chen J,Chen Q,Chen JY,et al. Magnetic carbon nitride nanocomposites as enhanced peroxidase mimetics for use in colorimetric bioassays, and their application to the determination of H2O2 and glucose[J]. Microchimica Acta,2016,183(12):3191-3199. |
APA | Chen J,Chen Q,Chen JY,Qiu HD,&邱洪灯.(2016).Magnetic carbon nitride nanocomposites as enhanced peroxidase mimetics for use in colorimetric bioassays, and their application to the determination of H2O2 and glucose.Microchimica Acta,183(12),3191-3199. |
MLA | Chen J,et al."Magnetic carbon nitride nanocomposites as enhanced peroxidase mimetics for use in colorimetric bioassays, and their application to the determination of H2O2 and glucose".Microchimica Acta 183.12(2016):3191-3199. |
入库方式: OAI收割
来源:兰州化学物理研究所
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