中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Magnetic carbon nitride nanocomposites as enhanced peroxidase mimetics for use in colorimetric bioassays, and their application to the determination of H2O2 and glucose

文献类型:期刊论文

作者Chen J(陈佳)1; Chen Q(陈桥)1,2; Chen JY(陈俊英)2; Qiu HD(邱洪灯)1,3; Qiu HD(邱洪灯)
刊名Microchimica Acta
出版日期2016
卷号183期号:12页码:3191-3199
关键词Magnetic nanocomposites Enzyme mimetic Hydrogen peroxide Glucose Transmission electron microscopy X-ray diffractionFourier transform infrared spectroscopy X-ray photoelectron spectra Magnetization hysteresis loops
ISSN号0026-3672
通讯作者邱洪灯
英文摘要

Graphite-like carbon nitride − Fe3O4 magnetic nanocomposites were synthesized by a chemical co-precipitation method. The nanocomposites were characterized by transmission electron microscopy, X-ray diffraction, FTIR spectroscopy, X-ray photoelectron spectroscopy and magnetization hysteresis loops. The nanocomposites exhibit enhanced peroxidase-like activity (compared to that of graphite-like carbon nitride or Fe3O4 NPs). More specifically, they are capable of catalyzing the oxidation of different peroxidase substrates (such as TMB, ABTS or OPD) by H2O2 to produce the typical color reactions (blue, green or orange). The nanocomposites retain their magnetic properties and can be separated by an external magnet. On the basis of these findings, a highly sensitive and selective method was applied to the determination of H2O2 and glucose (by using glucose oxidase). It was successfully applied to the determination of glucose in (spiked) human serum. Compared to other nanomaterial-based peroxidase mimetics, the one described here provides distinctly higher sensitivity for both H2O2 and glucose, with detection limits as low as 0.3 μM and 0.25 μM, respectively.

学科主题分析化学与药物化学
收录类别SCI
资助信息the National Natural Science Foundation of China (no. 21405163);the Foundation for Sci&Tech Research Project of Gansu Province (No. 145RJYA271);the Funds for Distinguished Young Scientists of Gansu (1506RJDA281);the top priority program of “One-Three-Five” Strategic Planning of Lanzhou Institute of Chemical Physics, CAS
语种英语
WOS记录号WOS:000389194500013
源URL[http://210.77.64.217/handle/362003/20913]  
专题兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
兰州化学物理研究所_OSSO国家重点实验室
通讯作者Qiu HD(邱洪灯)
作者单位1.Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu ProvinceLanzhou Institute of Chemical Physics, Chinese Academy of Sciences Lanzhou China
2.School of Materials Science and Engineering, Key Laboratory for Advanced Technologies of Materials of the Ministry of Education Southwest Jiaotong University Chengdu China
3.State Key Laboratory for Oxo Synthesis and Selective OxidationLanzhou Institute of Chemical Physics, Chinese Academy of Sciences Lanzhou China
推荐引用方式
GB/T 7714
Chen J,Chen Q,Chen JY,et al. Magnetic carbon nitride nanocomposites as enhanced peroxidase mimetics for use in colorimetric bioassays, and their application to the determination of H2O2 and glucose[J]. Microchimica Acta,2016,183(12):3191-3199.
APA Chen J,Chen Q,Chen JY,Qiu HD,&邱洪灯.(2016).Magnetic carbon nitride nanocomposites as enhanced peroxidase mimetics for use in colorimetric bioassays, and their application to the determination of H2O2 and glucose.Microchimica Acta,183(12),3191-3199.
MLA Chen J,et al."Magnetic carbon nitride nanocomposites as enhanced peroxidase mimetics for use in colorimetric bioassays, and their application to the determination of H2O2 and glucose".Microchimica Acta 183.12(2016):3191-3199.

入库方式: OAI收割

来源:兰州化学物理研究所

浏览0
下载0
收藏0
其他版本

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。