Sheathless Focusing and Separation of Diverse Nanoparticles in Viscoelastic Solutions with Minimized Shear Thinning
文献类型：期刊论文
| 作者 | Liu C; Ding BQ; Xue CD; Tian Y; Hu GQ(胡国庆) ; Su JS
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| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2016 |
| 卷号 | 88期号:24页码:12547-12553 |
| 通讯作者邮箱 | guoqing.hu@imech.ac.cn ; sunjs@nanoctr.cn |
| ISSN号 | 0003-2700 |
| 产权排序 | [Liu, Chao; Xue, Chundong; Hu, Guoqing] Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China; [Liu, Chao; Xue, Chundong; Hu, Guoqing] Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China; [Liu, Chao; Ding, Baoquan; Su, Jiashu] Natl Ctr NanoSci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China; [Tian, Yu] Tsinghua Univ, State Key Lab Tribol, Beijing 100084, Peoples R China |
| 通讯作者 | Hu, GQ (reprint author), Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China. ; Hu, GQ (reprint author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China. ; Su, JS (reprint author), Natl Ctr NanoSci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China. |
| 中文摘要 | Viscoelastic microfluidics becomes an efficient and label free hydrodynamic technology to enrich and separate micrometer-scale particles, including blood cells, circulating tumor cells, and bacteria. However, the manipulation of nanoscale particles by viscoelastic microfluidics remains a major challenge, because the viscoelastic force acting on the smaller particle decreases dramatically. In contrast to the commonly used polymer solutions of high molecular weight, herein we utilize the aqueous solutions of poly(ethylene oxide) (PEO) of low molecular weight with minimized shear thinning but sufficient elastic force for high-quality focusing and separation of various nanoparticles. The focusing efficiencies of 100 nm polystyrene (PS) nanoparticles and 2-DNA molecules are 84% and 85%, respectively, in a double spiral microchannel, without the aid of sheath flows. Furthermore, we demonstrate the size-based viscoelastic separation of two sets of binary mixtures-100/2000 nm PS particles and 2-DNA molecules/blood platelets all achieving separation efficiencies of >95% in the same device. Our proposal technique would be a promising approach for enrichment/separation of the nanoparticles encountered in applications of analytical chemistry and nanotechnology. |
| 分类号 | 一类 |
| 类目[WOS] | Chemistry, Analytical |
| 研究领域[WOS] | Chemistry |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/acs.analchem.6b04564 |
| 语种 | 英语 |
| WOS记录号 | WOS:000390621000078 |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/59974]  |
| 专题 | 力学研究所_非线性力学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Liu C,Ding BQ,Xue CD,et al. Sheathless Focusing and Separation of Diverse Nanoparticles in Viscoelastic Solutions with Minimized Shear Thinning[J]. ANALYTICAL CHEMISTRY,2016,88(24):12547-12553. |
| APA | Liu C,Ding BQ,Xue CD,Tian Y,胡国庆,&Su JS.(2016).Sheathless Focusing and Separation of Diverse Nanoparticles in Viscoelastic Solutions with Minimized Shear Thinning.ANALYTICAL CHEMISTRY,88(24),12547-12553. |
| MLA | Liu C,et al."Sheathless Focusing and Separation of Diverse Nanoparticles in Viscoelastic Solutions with Minimized Shear Thinning".ANALYTICAL CHEMISTRY 88.24(2016):12547-12553. |
入库方式： OAI收割
来源：力学研究所
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