Reversible Fluorescent Probe for Selective Detection and Cell Imaging of Oxidative Stress Indicator Bisulfite
文献类型：期刊论文
| 作者 | Zhang, Yajiao1,2; Guan, Lingmei4; Yu, Huan1,2; Yan, Yehan1,2; Du, Libo4; Liu, Yang4; Sun, Mingtai1,2; Huang, Dejian3; Wang, Suhua1,2 |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2016-04-19 |
| 卷号 | 88期号:8页码:4426-4431 |
| 英文摘要 | In this paper, we report a benzothiazole-functionalized cyanine fluorescence probe and demonstrate that it is selectively reactive to bisulfite, an intermediate indicator for oxidative stress. The selective reaction can be monitored by distinct ratiometric fluorescence variation favorable for cell imaging and visualization. The original probe can be regenerated in high yield through the elimination of bisulfite from the product by peroxides such as hydrogen peroxide, accompanied by fluorescence turning on at 590 nm, showing a potential application for the detection of peroxides. We successfully applied this probe for fluorescence imaging of bisulfite in cancer cells (MCF-7) treated with bisulfite and hydrogen peroxide as well as a selective detection limit of 0.34 mu M bisulfite in aqueous solution. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/36082]  |
| 专题 | 化学研究所_分子动态与稳态结构实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Intelligent Machines, Hefei 230031, Anhui, Peoples R China 2.Univ Sci & Technol China, Dept Mat Sci & Engn, Hefei 230026, Anhui, Peoples R China 3.Natl Univ Singapore, Dept Chem, Food Sci & Technol Programme, 3 Sci Dr 3, Singapore 117543, Singapore 4.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Yajiao,Guan, Lingmei,Yu, Huan,et al. Reversible Fluorescent Probe for Selective Detection and Cell Imaging of Oxidative Stress Indicator Bisulfite[J]. ANALYTICAL CHEMISTRY,2016,88(8):4426-4431. |
| APA | Zhang, Yajiao.,Guan, Lingmei.,Yu, Huan.,Yan, Yehan.,Du, Libo.,...&Wang, Suhua.(2016).Reversible Fluorescent Probe for Selective Detection and Cell Imaging of Oxidative Stress Indicator Bisulfite.ANALYTICAL CHEMISTRY,88(8),4426-4431. |
| MLA | Zhang, Yajiao,et al."Reversible Fluorescent Probe for Selective Detection and Cell Imaging of Oxidative Stress Indicator Bisulfite".ANALYTICAL CHEMISTRY 88.8(2016):4426-4431. |
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来源：化学研究所
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