Super-resolution imaging and tracking of TGF-beta receptor II on living cells
文献类型:期刊论文
作者 | Ye, Zi; Li, Nan; Zhao, Libo; Sun, Yahong; Ruan, Hefei; Zhang, Mingliang; Yuan, Jinghe; Fang, Xiaohong |
刊名 | SCIENCE BULLETIN
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出版日期 | 2016-04-01 |
卷号 | 61期号:8页码:632-638 |
关键词 | Single-particle tracking Photoactivated localization microscopy Single-molecule fluorescence imaging TGF-beta receptor II Membrane diffusion |
英文摘要 | Single-particle tracking photoactivated localization microscopy (sptPALM) has recently emerged as a powerful tool for high-density imaging and tracking of individual molecules in living cells. In this work, we have monitored and compared the diffusion dynamics of TGF-beta type II receptor (T beta RII) at high expression level using both traditional single-particle tracking (SPT) and sptPALM. The ligand-induced aggregation of TbRII oligomers was further indicated by sptPALM. Due to the capacity of distinguishing and tracking single molecules within diffraction limit, sptPALM outperforms traditional SPT by providing more accurate biophysical information. |
收录类别 | SCI |
语种 | 英语 |
源URL | [http://ir.iccas.ac.cn/handle/121111/36033] ![]() |
专题 | 化学研究所_分子纳米结构与纳米技术实验室 |
作者单位 | Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, Key Lab Mol Nanostruct & Nanotechnol, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Ye, Zi,Li, Nan,Zhao, Libo,et al. Super-resolution imaging and tracking of TGF-beta receptor II on living cells[J]. SCIENCE BULLETIN,2016,61(8):632-638. |
APA | Ye, Zi.,Li, Nan.,Zhao, Libo.,Sun, Yahong.,Ruan, Hefei.,...&Fang, Xiaohong.(2016).Super-resolution imaging and tracking of TGF-beta receptor II on living cells.SCIENCE BULLETIN,61(8),632-638. |
MLA | Ye, Zi,et al."Super-resolution imaging and tracking of TGF-beta receptor II on living cells".SCIENCE BULLETIN 61.8(2016):632-638. |
入库方式: OAI收割
来源:化学研究所
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