Asymmetric Retro-Claisen Reaction by Chiral Primary Amine Catalysis
文献类型：期刊论文
| 作者 | Zhu, Yunbo1,2; Zhang, Long1,2; Luo, Sanzhong1,2 |
| 刊名 | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
 |
| 出版日期 | 2016-03-30 |
| 卷号 | 138期号:12页码:3978-3981 |
| 英文摘要 | The communication describes an enamine-based asymmetric retro-Claisen reaction of beta-diketones by primary amine catalysis. The reaction proceeds via a sequence of stereoselective C-C formation, C-C cleavage, and a highly stereospecific enamine protonation to afford chiral alpha-alkylated ketones or macrolides with high yields and enantioselectivities. A detailed mechanism was explored on the basis of experimental evidence and computational studies to account for the observed stereo control. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/35995]  |
| 专题 | 化学研究所_分子识别与功能实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Key Lab Mol Recognit & Funct, BNLMS, Beijing 100190, Peoples R China 2.Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Yunbo,Zhang, Long,Luo, Sanzhong. Asymmetric Retro-Claisen Reaction by Chiral Primary Amine Catalysis[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2016,138(12):3978-3981. |
| APA | Zhu, Yunbo,Zhang, Long,&Luo, Sanzhong.(2016).Asymmetric Retro-Claisen Reaction by Chiral Primary Amine Catalysis.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,138(12),3978-3981. |
| MLA | Zhu, Yunbo,et al."Asymmetric Retro-Claisen Reaction by Chiral Primary Amine Catalysis".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 138.12(2016):3978-3981. |
入库方式： OAI收割
来源：化学研究所
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