中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 化学研究所
  3. 中国科学院化学研究所
  4. 分子识别与功能实验室
Iron-Carbonyl-Catalyzed Redox-Neutral [4+2] Annulation of N-H Imines and Internal Alkynes by C-H Bond Activation

文献类型：期刊论文

作者Jia, Teng1; Zhao, Chongyang2; He, Ruoyu1; Chen, Hui2; Wang, Congyang1
刊名ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
出版日期2016-04-18
卷号55期号:17页码:5268-5271
关键词alkynes annulations C-H activation heterocycles iron
英文摘要Stoichiometric C-H bond activation of arenes mediated by iron carbonyls was reported by Pauson as early as in 1965, yet the catalytic C-H transformations have not been developed. Herein, an iron-catalyzed annulation of N-H imines and internal alkynes to furnish cis-3,4-dihydroisoquinolines is described, and represents the first iron-carbonyl-catalyzed C-H activation reaction of arenes. Remarkablely, this is also the first redox-neutral [4+2] annulation of imines and alkynes proceeding by C-H activation. The reaction also features only cisstereoselectivity and excellent atom economy as neither base, nor external ligand, nor additive is required. Experimental and theoretical studies reveal an oxidative addition mechanism for C-H bond activation to afford a dinuclear ferracycle and a synergetic diiron-promoted H-transfer to the alkyne as the turnover-determining step.
收录类别SCI
语种英语
源URL[http://ir.iccas.ac.cn/handle/121111/36024]  
专题化学研究所_分子识别与功能实验室
作者单位1.Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, BNLMS, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Inst Chem, CAS Key Lab Photochem, BNLMS, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714		 Jia, Teng,Zhao, Chongyang,He, Ruoyu,et al. Iron-Carbonyl-Catalyzed Redox-Neutral [4+2] Annulation of N-H Imines and Internal Alkynes by C-H Bond Activation[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2016,55(17):5268-5271.
APA Jia, Teng,Zhao, Chongyang,He, Ruoyu,Chen, Hui,&Wang, Congyang.(2016).Iron-Carbonyl-Catalyzed Redox-Neutral [4+2] Annulation of N-H Imines and Internal Alkynes by C-H Bond Activation.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,55(17),5268-5271.
MLA Jia, Teng,et al."Iron-Carbonyl-Catalyzed Redox-Neutral [4+2] Annulation of N-H Imines and Internal Alkynes by C-H Bond Activation".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 55.17(2016):5268-5271.

入库方式： OAI收割

来源：化学研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。