Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars
文献类型：期刊论文
| 作者 | Qian, Bao-Chen1,5; Kamori, Akiko2; Kinami, Kyoko2; Kato, Atsushi2; Li, Yi-Xian1; Fleet, George W. J.3,4; Yu, Chu-Yi1,4 |
| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
 |
| 出版日期 | 2016 |
| 卷号 | 14期号:19页码:4488-4498 |
| 英文摘要 | Epimerization of C5 of an N-hydroxypyrrolidine ring by regioselective oxidation to a nitrone followed by diastereoselective reduction provides a new approach to the synthesis of swainsonine and related compounds. The only protection in the synthesis of the potent mannosidase inhibitor DIM (1,4-dideoxy-1,4-imino-D-mannitol) was the acetonation of D-mannose. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/36130]  |
| 专题 | 化学研究所_分子识别与功能实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, BNLMS, Beijing 100190, Peoples R China 2.Toyama Univ, Dept Hosp Pharm, 2630 Sugitani, Toyama 9300194, Japan 3.Univ Oxford, Dept Chem, Chem Res Lab, Mansfield Rd, Oxford OX1 3TA, England 4.Jiangxi Normal Univ, Natl Engn Res Ctr Carbohydrate Synth, Nanchang 330022, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qian, Bao-Chen,Kamori, Akiko,Kinami, Kyoko,et al. Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2016,14(19):4488-4498. |
| APA | Qian, Bao-Chen.,Kamori, Akiko.,Kinami, Kyoko.,Kato, Atsushi.,Li, Yi-Xian.,...&Yu, Chu-Yi.(2016).Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars.ORGANIC & BIOMOLECULAR CHEMISTRY,14(19),4488-4498. |
| MLA | Qian, Bao-Chen,et al."Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars".ORGANIC & BIOMOLECULAR CHEMISTRY 14.19(2016):4488-4498. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。