Facile fabrication of robust polydopamine microcapsules for insulin delivery
文献类型：期刊论文
| 作者 | Li, Hong1; Jia, Yi2; Feng, Xiyun2; Li, Junbai2 |
| 刊名 | JOURNAL OF COLLOID AND INTERFACE SCIENCE
 |
| 出版日期 | 2017-02-01 |
| 卷号 | 487页码:12-19 |
| 关键词 | Polydopamine microcapsules Oxidative self-polymerization Insulin pH-responsive release |
| 英文摘要 | Inspired by the composition of adhesive proteins in mussel, a facile, low-cost, and green approach to construct robust polydopamine (PDA) microcapsules as carriers for insulin delivery is developed. The morphology and shell thickness of the capsules could be tuned by varying the concentration of dopamine or the pH of Tris-HCI buffer. The PDA capsules are stable enough for long-term storage and transportation in practical application. The fluorescent property of PDA capsules labeled with FITC is beneficial in monitoring the safety and efficacy of drug carriers. Furthermore, the PDA shell coated insulin particles exhibit pH-responsive release behavior, making them promising for the oral administration of insulin in diabetic patients. (C) 2016 Elsevier Inc. All rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/35692]  |
| 专题 | 化学研究所_胶体、界面与化学热力学实验室 |
| 作者单位 | 1.Xian Shiyou Univ, Sch Chem & Chem Engn, Xian 710065, Peoples R China 2.Chinese Acad Sci, Inst Chem, Key Lab Colloid Interface & Chem Thermodynam, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Hong,Jia, Yi,Feng, Xiyun,et al. Facile fabrication of robust polydopamine microcapsules for insulin delivery[J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE,2017,487:12-19. |
| APA | Li, Hong,Jia, Yi,Feng, Xiyun,&Li, Junbai.(2017).Facile fabrication of robust polydopamine microcapsules for insulin delivery.JOURNAL OF COLLOID AND INTERFACE SCIENCE,487,12-19. |
| MLA | Li, Hong,et al."Facile fabrication of robust polydopamine microcapsules for insulin delivery".JOURNAL OF COLLOID AND INTERFACE SCIENCE 487(2017):12-19. |
入库方式： OAI收割
来源：化学研究所
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