Fabrication of Mesoporous Silica Nanoparticle with Well-Defined Multicompartment Structure as Efficient Drug Carrier for Cancer Therapy in Vitro and in Vivo
文献类型：期刊论文
| 作者 | Wang, Anhe1; Yang, Yang1; Qi, Yanfei3; Qi, Wen3; Fei, Jinbo2; Ma, Hongchao2; Zhao, Jie2; Cui, Wei2; Li, Junbai1,2 |
| 刊名 | ACS APPLIED MATERIALS & INTERFACES
 |
| 出版日期 | 2016-04-13 |
| 卷号 | 8期号:14页码:8900-8907 |
| 关键词 | silica particles vaterite particles multicompartment structure drug carrier cancer therapy |
| 英文摘要 | Vaterite particles are composed of particulate CaCO3 nano particles, which offer an ideal platform to synthesize architectures with hierarchical structure. Herein we show that mesoporous silica particles with well-defined multicompartment structure are fabricated by employing vaterite particles as templates. The obtained silica particles inherited the structure feature of vaterite and had excellent biocompatibility and biodegradability. Moreover, the silica particles were established as an efficient anticancer drugs carrier compared with hollow silica particles, which could be applied in cancer therapy in vitro and in vivo. The silica particles obtained here offer a cheap, facile, environmentally friendly avenue to assembly of hierarchical drugs carriers. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/36104]  |
| 专题 | 化学研究所_胶体、界面与化学热力学实验室 |
| 作者单位 | 1.Natl Ctr Nanosci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Chem, Key Lab Colloid & Interface Sci, BNLMS, Beijing 100190, Peoples R China 3.Jilin Univ, Sch Publ Hlth, Changchun 130021, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Anhe,Yang, Yang,Qi, Yanfei,et al. Fabrication of Mesoporous Silica Nanoparticle with Well-Defined Multicompartment Structure as Efficient Drug Carrier for Cancer Therapy in Vitro and in Vivo[J]. ACS APPLIED MATERIALS & INTERFACES,2016,8(14):8900-8907. |
| APA | Wang, Anhe.,Yang, Yang.,Qi, Yanfei.,Qi, Wen.,Fei, Jinbo.,...&Li, Junbai.(2016).Fabrication of Mesoporous Silica Nanoparticle with Well-Defined Multicompartment Structure as Efficient Drug Carrier for Cancer Therapy in Vitro and in Vivo.ACS APPLIED MATERIALS & INTERFACES,8(14),8900-8907. |
| MLA | Wang, Anhe,et al."Fabrication of Mesoporous Silica Nanoparticle with Well-Defined Multicompartment Structure as Efficient Drug Carrier for Cancer Therapy in Vitro and in Vivo".ACS APPLIED MATERIALS & INTERFACES 8.14(2016):8900-8907. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。