Fabrication of a mercaptoacetic acid pillar[5]arene assembled nanochannel: a biomimetic gate for mercury poisoning
文献类型：期刊论文
| 作者 | Zhang, Fan1; Ma, Junkai1; Sun, Yue1; Boussouar, Imene1; Tian, Demei1; Li, Haibing1,2; Jiang, Lei2 |
| 刊名 | CHEMICAL SCIENCE
 |
| 出版日期 | 2016 |
| 卷号 | 7期号:5页码:3227-3233 |
| 英文摘要 | Mercury ion binding blocks potassium ion channels, which leads to toxicity in vivo. It is challenging to design a simple and efficient artificial system to mimic the sophisticated biological process of mercury poisoning. Herein, based on biomimetic strategies, a tunable mercury(II) ion-gate modulated by mercaptoacetic acid-pillar[5] arene (MAP5) is reported. By virtue of the unique design of the host-guest competition, potassium ion transport can actualize the reversible switching between "on" and "off" in the absence and presence of mercury ions. Moreover, the MAP5-immobilized nanochannel is highly effective at distinguishing Hg2+ from other metal ions and can be used to detect Hg2+ and act as an excellent and robust gate valve for developing integrated circuits and nanoelectronic logic devices. This study paves a new way for better understanding the physiological phenomenon of mercury toxicity and shows great promise for biomedical research. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/36038]  |
| 专题 | 化学研究所_有机固体实验室 |
| 作者单位 | 1.Cent China Normal Univ, Minist Educ, Coll Chem, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Peoples R China 2.Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, BNLMS, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Fan,Ma, Junkai,Sun, Yue,et al. Fabrication of a mercaptoacetic acid pillar[5]arene assembled nanochannel: a biomimetic gate for mercury poisoning[J]. CHEMICAL SCIENCE,2016,7(5):3227-3233. |
| APA | Zhang, Fan.,Ma, Junkai.,Sun, Yue.,Boussouar, Imene.,Tian, Demei.,...&Jiang, Lei.(2016).Fabrication of a mercaptoacetic acid pillar[5]arene assembled nanochannel: a biomimetic gate for mercury poisoning.CHEMICAL SCIENCE,7(5),3227-3233. |
| MLA | Zhang, Fan,et al."Fabrication of a mercaptoacetic acid pillar[5]arene assembled nanochannel: a biomimetic gate for mercury poisoning".CHEMICAL SCIENCE 7.5(2016):3227-3233. |
入库方式： OAI收割
来源：化学研究所
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