Asymmetric Annulation of Donor-Acceptor Cyclopropanes with Dienes
文献类型：期刊论文
| 作者 | Xu H(徐浩)1; Hu JL(胡江林)1; Wang LJ(王丽佳)1; Liao SH(廖赛虎)1; Tang Y(唐勇)1 |
| 刊名 | J. Am. Chem. Soc.
 |
| 出版日期 | 2015 |
| 卷号 | 137期号:25页码:8006-8009 |
| 其他题名 | 推拉电子环丙烷与共轭二烯的不对称环化反应 |
| 通讯作者 | 唐勇 |
| 英文摘要 | An efficient [4 + 3] cycloaddition reaction of D-A cyclopropanes with dienes has been successfully developed. The reaction proceeds well with various dienolsilyl ethers in the presence of Lewis acid, delivering a variety of cycloheptenes and [n,5,0]carbobicycles with excellent stereoselectivity. The asymmetric version of this reaction is also realized using a newly designed chiral Cy-TOX ligand, providing a new approach to access optically active cycloheptenes and [n,5,0]carbobicycles. Mechanisic study reveals that the reaction involves a stepwise pathway, which undergoes an unusual ring opening of five-membered [3 + 2] intermediate and sequential intramolecular cyclization to afford the thermodynamically stable [4 + 3] annulation product. |
| 学科主题 | 金属有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/jacs.5b04429 |
| 语种 | 英语 |
| WOS记录号 | WOS:000357436300012 |
| 源URL | [http://ir.sioc.ac.cn/handle/331003/39623]  |
| 专题 | 上海有机化学研究所_金属有机化学国家重点实验室 |
| 作者单位 | 1.中科院上海有机化学研究所, 金属有机化学国家重点实验室 2.天津化学化工协同创新中心 |
| 推荐引用方式 GB/T 7714 | Xu H,Hu JL,Wang LJ,et al. Asymmetric Annulation of Donor-Acceptor Cyclopropanes with Dienes[J]. J. Am. Chem. Soc.,2015,137(25):8006-8009. |
| APA | 徐浩,胡江林,王丽佳,廖赛虎,&唐勇.(2015).Asymmetric Annulation of Donor-Acceptor Cyclopropanes with Dienes.J. Am. Chem. Soc.,137(25),8006-8009. |
| MLA | 徐浩,et al."Asymmetric Annulation of Donor-Acceptor Cyclopropanes with Dienes".J. Am. Chem. Soc. 137.25(2015):8006-8009. |
入库方式： OAI收割
来源：上海有机化学研究所
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