Enantioselective Construction of Spiroindolines with Three Contiguous Stereogenic Centers and Chiral Tryptamine Derivatives via Reactive Spiroindolenine Intermediates
文献类型：期刊论文
| 作者 | Zhuo CX(卓春祥)1; Zhou Y(周勇)1; Cheng Q(程强)1; Huang L(黄林)1; You SL(游书力)1 |
| 刊名 | Angew. Chem.-Int. Edit.
 |
| 出版日期 | 2015 |
| 卷号 | 54期号:47页码:14146-14149 |
| 其他题名 | 含有三个连续手性中心的螺吲哚啉以及通过活性螺吲哚啉中间体对于色胺衍生物的不对称构建 |
| 通讯作者 | 游书力 |
| 英文摘要 | The highly efficient synthesis of the enantioenriched spiroindolines by iridium-catalyzed asymmetric allylic dearomatization and reduction is presented. Spiroindolines containing three contiguous stereogenic centers were obtained with excellent diastereo- and enantioselectivity. In addition, a chiral tryptamine derivative could be easily accessed in good yield with excellent ee value through an unprecedented dearomatization/retro-Mannich/hydrolysis cascade reaction of an indole derivative. |
| 学科主题 | 金属有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1002/anie.201507193 |
| 语种 | 英语 |
| WOS记录号 | WOS:000367722500057 |
| 源URL | [http://ir.sioc.ac.cn/handle/331003/39684]  |
| 专题 | 上海有机化学研究所_金属有机化学国家重点实验室 |
| 作者单位 | 1.中科院上海有机化学研究所, 金属有机化学国家重点实验室 2.天津化学化工协同创新中心 |
| 推荐引用方式 GB/T 7714 | Zhuo CX,Zhou Y,Cheng Q,et al. Enantioselective Construction of Spiroindolines with Three Contiguous Stereogenic Centers and Chiral Tryptamine Derivatives via Reactive Spiroindolenine Intermediates[J]. Angew. Chem.-Int. Edit.,2015,54(47):14146-14149. |
| APA | 卓春祥,周勇,程强,黄林,&游书力.(2015).Enantioselective Construction of Spiroindolines with Three Contiguous Stereogenic Centers and Chiral Tryptamine Derivatives via Reactive Spiroindolenine Intermediates.Angew. Chem.-Int. Edit.,54(47),14146-14149. |
| MLA | 卓春祥,et al."Enantioselective Construction of Spiroindolines with Three Contiguous Stereogenic Centers and Chiral Tryptamine Derivatives via Reactive Spiroindolenine Intermediates".Angew. Chem.-Int. Edit. 54.47(2015):14146-14149. |
入库方式： OAI收割
来源：上海有机化学研究所
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