O-Glycosylation methods in the total synthesis of complex natural glycosides
文献类型：期刊论文
| 作者 | Yang Y(杨友)1; Zhang XH(张夏衡)1; Yu B(俞飚)1 |
| 刊名 | Nat. Prod. Rep.
 |
| 出版日期 | 2015 |
| 卷号 | 32期号:9页码:1331-1355 |
| 其他题名 | 氧-糖苷化在天然糖苷类化合物合成中的应用 |
| 通讯作者 | 杨友 ; 俞飚 |
| 英文摘要 | The total syntheses of 33 complex natural O-glycosides, such as the glycosides of macrocyclic lactones/lactams, enediynes, angucyclines, and anthracyclines, are highlighted, with a major focus being placed on the O-glycosylation reactions which connect the saccharides and the aglycones. These successful O-glycosylation reactions employ such donors as glycosyl bromides, fluorides, iodides, trichloroacetimidates, N-phenyl trifluoroacetimidates, thioglycosides, sulfoxides, heteroaryl thioglycosides, 1-hydroxyl sugars, 1-O-acetates, and ortho-alkynylbenzoates. Each synthesis is depicted starting from the O-glycosylation of the aglycone (or its precursor); the glycosylation conditions and outcomes (yields and stereoselectivities) are discussed, and the subsequent transformations toward the final target, including the elongation of the glycan, the elaboration of the aglycone, and the protecting group manipulations are also given in detail. |
| 学科主题 | 生命有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1039/c5np00033e |
| 语种 | 英语 |
| WOS记录号 | WOS:000360115000004 |
| 源URL | [http://ir.sioc.ac.cn/handle/331003/39523]  |
| 专题 | 上海有机化学研究所_生命有机化学国家重点实验室 |
| 作者单位 | 1.华东理工大学 2.中科院上海有机化学研究所, 生命有机化学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Yang Y,Zhang XH,Yu B. O-Glycosylation methods in the total synthesis of complex natural glycosides[J]. Nat. Prod. Rep.,2015,32(9):1331-1355. |
| APA | 杨友,张夏衡,&俞飚.(2015).O-Glycosylation methods in the total synthesis of complex natural glycosides.Nat. Prod. Rep.,32(9),1331-1355. |
| MLA | 杨友,et al."O-Glycosylation methods in the total synthesis of complex natural glycosides".Nat. Prod. Rep. 32.9(2015):1331-1355. |
入库方式： OAI收割
来源：上海有机化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。