AgF-Mediated Fluorinative Cross-Coupling of Two Olefins: Facile Access to alpha-CF3 Alkenes and beta-CF3 Ketones
文献类型：期刊论文
| 作者 | Gao B(高兵); Zhao YC(赵延川); Hu JB(胡金波) |
| 刊名 | Angew. Chem.-Int. Edit.
 |
| 出版日期 | 2015 |
| 卷号 | 54期号:2页码:638-642 |
| 其他题名 | 氟化银促进的双烯烃氟化交叉偶联反应: 一种便捷合成α-三氟甲基烯烃和 β-三氟甲基酮的方法 |
| 通讯作者 | 胡金波 |
| 英文摘要 | A AgF-mediated fluorination with a concomitant cross-coupling between a gem-difluoroolefin and a non-fluorinated olefin is reported. This highly efficient method provides facile access to both -CF3 alkenes and -CF3 ketones, which otherwise remain challenging to be directly prepared. The application of this method is further demonstrated by the synthesis of bioactive isoxazoline derivatives. This approach represents a conceptually novel route to trifluoromethylated compounds that combines the insitu generation of the CF3 moiety and a CH functionalization in a single reaction system. |
| 学科主题 | 氟化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1002/anie.201409705 |
| 语种 | 英语 |
| WOS记录号 | WOS:000347238800046 |
| 源URL | [http://ir.sioc.ac.cn/handle/331003/39700]  |
| 专题 | 上海有机化学研究所_中科院有机氟化学重点实验室 |
| 作者单位 | 中科院上海有机化学研究所, 有机氟化学重点实验室 |
| 推荐引用方式 GB/T 7714 | Gao B,Zhao YC,Hu JB. AgF-Mediated Fluorinative Cross-Coupling of Two Olefins: Facile Access to alpha-CF3 Alkenes and beta-CF3 Ketones[J]. Angew. Chem.-Int. Edit.,2015,54(2):638-642. |
| APA | 高兵,赵延川,&胡金波.(2015).AgF-Mediated Fluorinative Cross-Coupling of Two Olefins: Facile Access to alpha-CF3 Alkenes and beta-CF3 Ketones.Angew. Chem.-Int. Edit.,54(2),638-642. |
| MLA | 高兵,et al."AgF-Mediated Fluorinative Cross-Coupling of Two Olefins: Facile Access to alpha-CF3 Alkenes and beta-CF3 Ketones".Angew. Chem.-Int. Edit. 54.2(2015):638-642. |
入库方式： OAI收割
来源：上海有机化学研究所
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