N-Difluoromethylthiophthalimide: A Shelf-Stable, Electrophilic Reagent for Difluoromethylthiolation
文献类型：期刊论文
| 作者 | Zhu DH(朱佃虎); Gu Y(古阳); Lv L(吕龙); Shen QL(沈其龙) |
| 刊名 | J. Am. Chem. Soc.
 |
| 出版日期 | 2015 |
| 卷号 | 137期号:33页码:10547-10553 |
| 其他题名 | N-二氟甲硫基邻苯酰亚胺: 一个稳定的亲电二氟甲硫基试剂 |
| 通讯作者 | 吕龙 ; 沈其龙 |
| 英文摘要 | A new, electrophilic difluoromethylthiolating reagent N-difluoromethylthiophthalimide 3 was developed. Reagent 3 can be readily synthesized in four steps from easily available starting materials phthalimide and TMSCF2H. N-difluoromethylthiophthalimide 3 is a powerful electrophilic difluoromethylthiolating reagent that allows the difluoromethylthiolation of a wide range of nucleophiles including aryl/vinyl boronic acids, alkynes, amines, thiols, beta-ketoesters, and oxindoles and electron-rich heteroarenes such as indole, pyrrole, 1H-pyrrolo[2,3-b]pyridine, imidazo[1,2-a]pyridine, aminothiazole, isoxazole, and pyrazole under mild conditions. |
| 学科主题 | 氟化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/jacs.5b03170 |
| 语种 | 英语 |
| WOS记录号 | WOS:000360321100025 |
| 源URL | [http://ir.sioc.ac.cn/handle/331003/39742]  |
| 专题 | 上海有机化学研究所_中科院有机氟化学重点实验室 |
| 作者单位 | 中科院上海有机化学研究所, 有机氟化学重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhu DH,Gu Y,Lv L,et al. N-Difluoromethylthiophthalimide: A Shelf-Stable, Electrophilic Reagent for Difluoromethylthiolation[J]. J. Am. Chem. Soc.,2015,137(33):10547-10553. |
| APA | 朱佃虎,古阳,吕龙,&沈其龙.(2015).N-Difluoromethylthiophthalimide: A Shelf-Stable, Electrophilic Reagent for Difluoromethylthiolation.J. Am. Chem. Soc.,137(33),10547-10553. |
| MLA | 朱佃虎,et al."N-Difluoromethylthiophthalimide: A Shelf-Stable, Electrophilic Reagent for Difluoromethylthiolation".J. Am. Chem. Soc. 137.33(2015):10547-10553. |
入库方式： OAI收割
来源：上海有机化学研究所
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