Analyses of genetic structure of Tibeto-Burman populations reveals sex-biased admixture in southern Tibeto-Burmans
文献类型：期刊论文
| 作者 | Wen B[*]1; Xie XH1; Gao S1; Li H1; Shi H2,3; Song XF1; Qian TZ1; Xiao CJ2; Jin JZ1; Su B3,4 |
| 刊名 | AMERICAN JOURNAL OF HUMAN GENETICS
 |
| 出版日期 | 2004 |
| 卷号 | 74期号:5页码:856-865 |
| ISSN号 | 0002-9297 |
| 通讯作者 | lijin@fudan.edu.cn ; li.jin@uc.edu |
| 合作状况 | 其它 |
| 英文摘要 | An unequal contribution of male and female lineages from parental populations to admixed ones is not uncommon in the American continents, as a consequence of directional gene flow from European men into African and Hispanic Americans in the past several centuries. However, little is known about sex-biased admixture in East Asia, where substantial migrations are recorded. Tibeto-Burman ( TB) populations were historically derived from ancient tribes of northwestern China and subsequently moved to the south, where they admixed with the southern natives during the past 2,600 years. They are currently extensively distributed in China and Southeast Asia. In this study, we analyze the variations of 965 Y chromosomes and 754 mtDNAs in >20 TB populations from China. By examining the haplotype group distributions of Y-chromosome and mtDNA markers and their principal components, we show that the genetic structure of the extant southern Tibeto-Burman (STB) populations were primarily formed by two parental groups: northern immigrants and native southerners. Furthermore, the admixture has a bias between male and female lineages, with a stronger influence of northern immigrants on the male lineages (similar to62%) and with the southern natives contributing more extensively to the female lineages (similar to56%) in the extant STBs. This is the first genetic evidence revealing sex-biased admixture in STB populations, which has genetic, historical, and anthropological implications. |
| 收录类别 | SCI |
| 资助信息 | This work is partially supported by Natural Science Foundation of China grant 39993420. L.J. is also supported by National Science FoundationgrantBCS-0213857,andL.J.and R.C. are supported by National Institutes of Health grant GM 41399. |
| 原文出处 | 200474856.pdf |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/2119]  |
| 专题 | 昆明动物研究所_比较基因组学 昆明动物研究所_细胞与分子进化重点实验室 |
| 作者单位 | 1.State Key Laboratory of Genetic Engineering and Center for Anthropological Studies, School of Life Sciences, Fudan University, Shanghai 2.Department of Biology and Human Genetics Center, Yunnan University 3.Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 4.Center for Genome Information, Department of Environmental Health, University of Cincinnati, Cincinnati |
| 推荐引用方式 GB/T 7714 | Wen B[*],Xie XH,Gao S,et al. Analyses of genetic structure of Tibeto-Burman populations reveals sex-biased admixture in southern Tibeto-Burmans[J]. AMERICAN JOURNAL OF HUMAN GENETICS,2004,74(5):856-865. |
| APA | Wen B[*].,Xie XH.,Gao S.,Li H.,Shi H.,...&Jin L[*].(2004).Analyses of genetic structure of Tibeto-Burman populations reveals sex-biased admixture in southern Tibeto-Burmans.AMERICAN JOURNAL OF HUMAN GENETICS,74(5),856-865. |
| MLA | Wen B[*],et al."Analyses of genetic structure of Tibeto-Burman populations reveals sex-biased admixture in southern Tibeto-Burmans".AMERICAN JOURNAL OF HUMAN GENETICS 74.5(2004):856-865. |
入库方式： OAI收割
来源：昆明动物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。