The ADH1B Arg47His polymorphism in East Asian populations and expansion of rice domestication in history
文献类型：期刊论文
| 作者 | Peng Y1,4; Shi H1; Qi XB1; Xiao CJ2; Zhong H3; Ma RLZ3; Su B[*]1 |
| 刊名 | BMC EVOLUTIONARY BIOLOGY
 |
| 出版日期 | 2010 |
| 卷号 | 10期号:X页码:e15 |
| ISSN号 | 1471-2148 |
| 通讯作者 | sub@mail.kiz.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Background: The emergence of agriculture about 10,000 years ago marks a dramatic change in human evolutionary history. The diet shift in agriculture societies might have a great impact on the genetic makeup of Neolithic human populations. The regionally restricted enrichment of the class I alcohol dehydrogenase sequence polymorphism (ADH1BArg47His) in southern China and the adjacent areas suggests Darwinian positive selection on this genetic locus during Neolithic time though the driving force is yet to be disclosed. Results: We studied a total of 38 populations (2,275 individuals) including Han Chinese, Tibetan and other ethnic populations across China. The geographic distribution of the ADH1B*47His allele in these populations indicates a clear east-to-west cline, and it is dominant in south-eastern populations but rare in Tibetan populations. The molecular dating suggests that the emergence of the ADH1B*47His allele occurred about 10,000 similar to 7,000 years ago. Conclusion: We present genetic evidence of selection on the ADH1BArg47His polymorphism caused by the emergence and expansion of rice domestication in East Asia. The geographic distribution of the ADH1B*47His allele in East Asia is consistent with the unearthed culture relic sites of rice domestication in China. The estimated origin time of ADH1B*47His allele in those populations coincides with the time of origin and expansion of Neolithic agriculture in southern China. |
| 收录类别 | SCI |
| 资助信息 | This study was supported by grants from the National 973 project of China (2007CB947701,2007CB815705), the Chinese Academy of Sciences (KSCX1- YW-R-34, Westlight Doctoral Program), the National Natural Science Foundation of China (30525028, 30700445, 30630013 and 30771181), and the Natural Science Foundation of Yunnan Province of China (2007C100M, 2009CD107). |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/2209]  |
| 专题 | 昆明动物研究所_比较基因组学 昆明动物研究所_遗传资源与进化国家重点实验室 昆明动物研究所_中国科学院昆明灵长类研究中心 |
| 作者单位 | 1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology and Kunming Primate Research Centre, Chinese Academy of Sciences, Kunming, China 2.Human Genetics Centre, School of Life Science, Yunnan University, Kunming, Chin 3.nstitute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China 4.Graduate School of Chinese Academy Sciences, Beijing, China |
| 推荐引用方式 GB/T 7714 | Peng Y,Shi H,Qi XB,et al. The ADH1B Arg47His polymorphism in East Asian populations and expansion of rice domestication in history[J]. BMC EVOLUTIONARY BIOLOGY,2010,10(X):e15. |
| APA | Peng Y.,Shi H.,Qi XB.,Xiao CJ.,Zhong H.,...&Su B[*].(2010).The ADH1B Arg47His polymorphism in East Asian populations and expansion of rice domestication in history.BMC EVOLUTIONARY BIOLOGY,10(X),e15. |
| MLA | Peng Y,et al."The ADH1B Arg47His polymorphism in East Asian populations and expansion of rice domestication in history".BMC EVOLUTIONARY BIOLOGY 10.X(2010):e15. |
入库方式： OAI收割
来源：昆明动物研究所
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