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Extended Y Chromosome Investigation Suggests Postglacial Migrations of Modern Humans into East Asia via the Northern Route
文献类型：期刊论文
| 作者 | Zhong H1,2,3; Shi H2; Qi XB2; Duan ZY4; Tan PP1; Jin L5; Su B[*]2; Ma RZ[*]1 |
| 刊名 | MOLECULAR BIOLOGY AND EVOLUTION
 |
| 出版日期 | 2011 |
| 卷号 | 28期号:1页码:717-727 |
| 关键词 | East Asia Y chromosome haplogroup Q haplogoup R postglacial migrations northern route |
| 通讯作者 | sub@mail.kiz.ac.cn ; rlma@genetics.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Genetic diversity data, from Y chromosome and mitochondrial DNA as well as recent genome-wide autosomal single nucleotide polymorphisms, suggested that mainland Southeast Asia was the major geographic source of East Asian populations. However, these studies also detected Central-South Asia (CSA)- and/or West Eurasia (WE)-related genetic components in East Asia, implying either recent population admixture or ancient migrations via the proposed northern route. To trace the time period and geographic source of these CSA- and WE-related genetic components, we sampled 3,826 males (116 populations from China and 1 population from North Korea) and performed high-resolution genotyping according to the well-resolved Y chromosome phylogeny. Our data, in combination with the published East Asian Y-haplogroup data, show that there are four dominant haplogroups (accounting for 92.87% of the East Asian Y chromosomes), O-M175, D-M174, C-M130 (not including C5-M356), and N-M231, in both southern and northern East Asian populations, which is consistent with the proposed southern route of modern human origin in East Asia. However, there are other haplogroups (6.79% in total) (E-SRY4064, C5-M356, G-M201, H-M69, I-M170, J-P209, L-M20, Q-M242, R-M207, and T-M70) detected primarily in northern East Asian populations and were identified as Central-South Asian and/or West Eurasian origin based on the phylogeographic analysis. In particular, evidence of geographic distribution and Y chromosome short tandem repeat (Y-STR) diversity indicates that haplogroup Q-M242 (the ancestral haplogroup of the native American-specific haplogroup Q1a3a-M3) and R-M207 probably migrated into East Asia via the northern route. The age estimation of Y-STR variation within haplogroups suggests the existence of postglacial (similar to 18 Ka) migrations via the northern route as well as recent (similar to 3 Ka) population admixture. We propose that although the Paleolithic migrations via the southern route played a major role in modern human settlement in East Asia, there are ancient contributions, though limited, from WE, which partly explain the genetic divergence between current southern and northern East Asian populations |
| 资助信息 | This study was supported by grants from the National 973 project of China (2007CB947701 and 2007CB815705), the Chinese Academy of Sciences (KSCX1-YW-R-34, Westlight Doctoral Pro- gram), the National Natural Science Foundation of China (30413242, 30771148, 30971566, 30700445, 30630013, and 30771181), and the Natural Science Foundation of Yunnan Province of China (2007C100M and 2009CD107). |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2011-03-15 |
| 源URL | [http://159.226.149.42:8088/handle/353002/6584]  |
| 专题 | 昆明动物研究所_比较基因组学 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.Center for Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China 2.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology and Kunming Primate Research Centre, Chinese Academy of Sciences, Kunming, China 3.Graduate School, Chinese Academy of Sciences, Beijing, China 4.Research Resources Center, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China 5.State Key Laboratory of Genetic Engineering and Center for Anthropological Studies, School of Life Sciences, Fudan University, Shanghai, China |
| 推荐引用方式 GB/T 7714 | Zhong H,Shi H,Qi XB,et al. Extended Y Chromosome Investigation Suggests Postglacial Migrations of Modern Humans into East Asia via the Northern Route[J]. MOLECULAR BIOLOGY AND EVOLUTION,2011,28(1):717-727. |
| APA | Zhong H.,Shi H.,Qi XB.,Duan ZY.,Tan PP.,...&Ma RZ[*].(2011).Extended Y Chromosome Investigation Suggests Postglacial Migrations of Modern Humans into East Asia via the Northern Route.MOLECULAR BIOLOGY AND EVOLUTION,28(1),717-727. |
| MLA | Zhong H,et al."Extended Y Chromosome Investigation Suggests Postglacial Migrations of Modern Humans into East Asia via the Northern Route".MOLECULAR BIOLOGY AND EVOLUTION 28.1(2011):717-727. |
入库方式： OAI收割
来源：昆明动物研究所
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